Cellular pharmacokinetic of methotrexate and its modulation by folylpolyglutamate synthetase and γ-glutamyl hydrolase in tumor cells

• Fang Tang,

  Roles Writing – original draft

  Affiliation Department of Pharmacy, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China

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• Le Zou,

  Roles Data curation, Formal analysis

  Affiliation Pharmacy Department, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong Province, China

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• Jingyao Chen,

  Roles Investigation, Software

  Affiliation Digestive Medicine Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China

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• Fanqi Meng

  Roles Writing – review & editing

  * E-mail: 197471179@qq.com

  Affiliation Pharmacy Department, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong Province, China

  https://orcid.org/0000-0001-6417-522X

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