Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)—Protocol for a randomised controlled exercise trial

• Justin Carrard ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: justin.carrard@chuv.ch, justin.carrard@unibas.ch

  Affiliations Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland, SportAdo Centre, Children and Adolescent Surgery, Woman-Mother-Child Department, Lausanne University Hospital, Lausanne, Switzerland

  https://orcid.org/0000-0002-2380-105X

  ⨯
• Manuel Hofer,

  Roles Conceptualization, Project administration, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  ⨯
• Luisa Prechtl,

  Roles Conceptualization, Methodology, Project administration, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  ⨯
• Eva Fleischlin,

  Roles Conceptualization, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  ⨯
• Manuel Huber,

  Roles Conceptualization, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  ⨯
• Hector Gallart-Ayala,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland

  ⨯
• Tony Teav,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland

  ⨯
• Denis Infanger,

  Roles Methodology, Software, Visualization, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  https://orcid.org/0000-0001-9028-7110

  ⨯
• Christoph Höchsmann,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Health and Sport Sciences, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany

  ⨯
• Karsten Koehler,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Health and Sport Sciences, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany

  ⨯
• Timo Hinrichs,

  Roles Methodology, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  ⨯
• Henner Hanssen,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  https://orcid.org/0000-0001-5501-4205

  ⨯
• Julijana Ivanisevic ,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  ¶‡ JI and AST are joint senior authors on this work.

  Affiliation Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland

  ⨯
• Arno Schmidt-Trucksäss

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  ¶‡ JI and AST are joint senior authors on this work.

  Affiliation Division of Sport and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland

  ⨯