Gut microbial diversity and functional characterization in people with alcohol use disorder: A case-control study

• Daria Piacentino ,

  Roles Data curation, Writing – original draft, Writing – review & editing

  ¶‡ DP, CV, and JJB are co-first authors on this work.

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

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• Carlotta Vizioli ,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  ¶‡ DP, CV, and JJB are co-first authors on this work.

  Affiliation Interoceptive Disorders Unit, Office of the Clinical Director, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, United States of America

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• Jennifer J. Barb ,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  ¶‡ DP, CV, and JJB are co-first authors on this work.

  Affiliation Translational Biobehavioral and Health Disparities Branch, Clinical Center, NIH, Bethesda, MD, United States of America

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• Silvia Grant-Beurmann,

  Roles Formal analysis, Methodology

  Affiliation Institute for Genome Sciences and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States of America

  https://orcid.org/0000-0001-5713-9212

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• Sofia Bouhlal,

  Roles Conceptualization, Investigation, Methodology, Resources

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

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• Jillian T. Battista,

  Roles Data curation, Methodology

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

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• Olivia Jennings,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

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• Mary R. Lee,

  Roles Investigation, Methodology, Project administration, Validation

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

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• Melanie L. Schwandt,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Bethesda, MD, United States of America

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• Peter Walter,

  Roles Formal analysis, Methodology

  Affiliation National Institute of Diabetes and Digestive and Kidney Diseases Division of Intramural Research, NIH, Bethesda, MD, United States of America

  https://orcid.org/0000-0001-8571-398X

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• Wendy A. Henderson,

  Roles Formal analysis, Methodology

  Affiliation Department of Biobehavioral Health Sciences, University of Pennsylvania School of Nursing, Philadelphia, PA, United States of America

  ⨯
• Kun Chen,

  Roles Formal analysis

  Affiliation Department of Statistics, University of Connecticut, Storrs, CT, United States of America

  https://orcid.org/0000-0003-3579-5467

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• Sara Turner,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Nutrition Department, Clinical Center, NIH, Bethesda, MD, United States of America

  ⨯
• Shanna Yang,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Nutrition Department, Clinical Center, NIH, Bethesda, MD, United States of America

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• Claire M. Fraser,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Institute for Genome Sciences and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States of America

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• Lisa A. Farinelli,

  Roles Data curation, Methodology, Project administration

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

  ⨯
• Mehdi Farokhnia,

  Roles Conceptualization, Data curation, Investigation, Supervision, Validation, Writing – review & editing

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

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•  [ ... ],
• Lorenzo Leggio

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: lorenzo.leggio@nih.gov

  Affiliation Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, NIH, Baltimore, MD, United States of America

  https://orcid.org/0000-0001-7284-8754

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