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Open Access

Peer-reviewed

Research Article

Transcutaneous carbon dioxide suppresses skeletal muscle atrophy in a mouse model of oral squamous cell carcinoma

Aki Sasaki ,

Contributed equally to this work with: Aki Sasaki, Daisuke Takeda, Hotaka Kawai

Roles Conceptualization, Data curation, Formal analysis, Validation, Writing – original draft

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan
⨯
Daisuke Takeda ,

Contributed equally to this work with: Aki Sasaki, Daisuke Takeda, Hotaka Kawai

Roles Conceptualization, Data curation, Formal analysis, Validation, Writing – original draft

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan

https://orcid.org/0009-0000-5878-8871

⨯
Hotaka Kawai ,

Contributed equally to this work with: Aki Sasaki, Daisuke Takeda, Hotaka Kawai

Roles Data curation, Formal analysis

Affiliation Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Yoshiaki Tadokoro,

Roles Investigation

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan
⨯
Aki Murakami,

Roles Investigation

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan
⨯
Nanae Yatagai,

Roles Investigation

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan
⨯
Satomi Arimoto,

Roles Investigation

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan
⨯
Hitoshi Nagatsuka,

Roles Supervision

Affiliation Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Masaya Akashi,

Roles Supervision

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan
⨯
Takumi Hasegawa

Roles Conceptualization, Writing – review & editing

* E-mail: hasetaku@med.kobe-u.ac.jp

Affiliation Department of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Japan

https://orcid.org/0000-0002-7349-7084

⨯

Transcutaneous carbon dioxide suppresses skeletal muscle atrophy in a mouse model of oral squamous cell carcinoma

Aki Sasaki,
Daisuke Takeda,
Hotaka Kawai,
Yoshiaki Tadokoro,
Aki Murakami,
Nanae Yatagai,
Satomi Arimoto,
Hitoshi Nagatsuka,
Masaya Akashi,
Takumi Hasegawa

x

Published: April 17, 2024
https://doi.org/10.1371/journal.pone.0302194

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Skeletal muscles
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Atrophy
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Cancers and neoplasms
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Cancer treatment
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Carbon dioxide
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Head and neck cancers
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Mouse models
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Muscle proteins
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