Immunogenic profile of a plant-produced nonavalent African horse sickness viral protein 2 (VP2) vaccine in IFNAR-/- mice

Martha M. O’Kennedy; Robyn Roth; Karen Ebersohn; Lissinda H. du Plessis; Sipho Mamputha; Daria A. Rutkowska; Ilse du Preez; Jan A. Verschoor; Yolandy Lemmer

doi:10.1371/journal.pone.0301340

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Open Access

Peer-reviewed

Research Article

Immunogenic profile of a plant-produced nonavalent African horse sickness viral protein 2 (VP2) vaccine in IFNAR^-/^-mice

Martha M. O’Kennedy ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft

* E-mail: mokennedy@csir.co.za

Affiliation Council for Scientific and Industrial Research (CSIR), Chemical Cluster, Pretoria, South Africa

https://orcid.org/0000-0003-3050-7008

⨯
Robyn Roth,

Roles Investigation, Methodology, Validation

Affiliation Council for Scientific and Industrial Research (CSIR), Chemical Cluster, Pretoria, South Africa
⨯
Karen Ebersohn,

Roles Data curation, Formal analysis, Methodology, Validation

Affiliation Department of Veterinary Tropical Diseases, University of Pretoria, Pretoria, South Africa
⨯
Lissinda H. du Plessis,

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Centre of Excellence for Pharmaceutical Sciences (PharmacenTM), North-West University, Potchefstroom, South Africa

https://orcid.org/0000-0003-0954-2976

⨯
Sipho Mamputha,

Roles Data curation, Formal analysis, Methodology

Affiliation Council for Scientific and Industrial Research (CSIR), Chemical Cluster, Pretoria, South Africa
⨯
Daria A. Rutkowska,

Roles Conceptualization, Writing – review & editing

Affiliation Council for Scientific and Industrial Research (CSIR), Chemical Cluster, Pretoria, South Africa
⨯
Ilse du Preez,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Council for Scientific and Industrial Research (CSIR), Chemical Cluster, Pretoria, South Africa
⨯
Jan A. Verschoor,

Roles Formal analysis, Writing – review & editing

Affiliation Department of Biochemistry, University of Pretoria, Pretoria, South Africa
⨯
Yolandy Lemmer

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Council for Scientific and Industrial Research (CSIR), Chemical Cluster, Pretoria, South Africa
⨯

Immunogenic profile of a plant-produced nonavalent African horse sickness viral protein 2 (VP2) vaccine in IFNAR^-/^-mice

Martha M. O’Kennedy,
Robyn Roth,
Karen Ebersohn,
Lissinda H. du Plessis,
Sipho Mamputha,
Daria A. Rutkowska,
Ilse du Preez,
Jan A. Verschoor,
Yolandy Lemmer

Published: April 16, 2024
https://doi.org/10.1371/journal.pone.0301340

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