In vitro anti-Helicobacter pylori activity and antivirulence activity of cetylpyridinium chloride

Mingjin Xun; Zhong Feng; Hui Li; Meicun Yao; Haibo Wang; Ruixia Wei; Junwei Jia; Zimao Fan; Xiaoyan Shi; Zhanzhu Lv; Guimin Zhang

doi:10.1371/journal.pone.0300696

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Open Access

Peer-reviewed

Research Article

In vitro anti-Helicobacter pylori activity and antivirulence activity of cetylpyridinium chloride

Mingjin Xun,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China

https://orcid.org/0000-0001-9536-8534

⨯
Zhong Feng ,

Roles Writing – original draft, Writing – review & editing

* E-mail: 13734352772@163.com (ZF); lunanzhangguimin@163.com (GZ)

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China, School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China
⨯
Hui Li,

Roles Writing – original draft, Writing – review & editing

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯
Meicun Yao,

Roles Conceptualization, Writing – review & editing

Affiliation School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China
⨯
Haibo Wang,

Roles Resources, Software, Supervision, Validation

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯
Ruixia Wei,

Roles Data curation, Formal analysis

Affiliation National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China
⨯
Junwei Jia,

Roles Writing – original draft, Writing – review & editing

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯
Zimao Fan,

Roles Data curation, Formal analysis, Methodology

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯
Xiaoyan Shi,

Roles Writing – original draft, Writing – review & editing

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯
Zhanzhu Lv,

Roles Writing – original draft, Writing – review & editing

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯
Guimin Zhang

Roles Funding acquisition

* E-mail: 13734352772@163.com (ZF); lunanzhangguimin@163.com (GZ)

Affiliations National Engineering and Technology Research Center of Chirality Pharmaceutical, Lunan Pharmaceutical Group Co., Ltd., Linyi, Shandong, China, International Pharmaceutical Engineering Laboratory in Shandong Province, Shandong New Time Pharmaceutical Co., Ltd., Linyi, Shandong, China
⨯

In vitro anti-Helicobacter pylori activity and antivirulence activity of cetylpyridinium chloride

Mingjin Xun,
Zhong Feng,
Hui Li,
Meicun Yao,
Haibo Wang,
Ruixia Wei,
Junwei Jia,
Zimao Fan,
Xiaoyan Shi,
Zhanzhu Lv

Published: April 11, 2024
https://doi.org/10.1371/journal.pone.0300696

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