Interpretable dimensionality reduction and classification of mass spectrometry imaging data in a visceral pain model via non-negative matrix factorization

• Kasun Pathirage ,

  Contributed equally to this work with: Kasun Pathirage, Aman Virmani

  Roles Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute for Systems Research, University of Maryland, College Park, Maryland, United States of America, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States of America

  https://orcid.org/0000-0002-6496-1148

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• Aman Virmani ,

  Contributed equally to this work with: Kasun Pathirage, Aman Virmani

  Roles Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute for Systems Research, University of Maryland, College Park, Maryland, United States of America, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States of America

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• Alison J. Scott,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbial Pathogenesis, University of Maryland, Baltimore, Maryland, United States of America

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• Richard J. Traub,

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Neural and Pain Sciences, University of Maryland School of Dentistry, Baltimore, Maryland, United States of America

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• Robert K. Ernst,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbial Pathogenesis, University of Maryland, Baltimore, Maryland, United States of America

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• Reza Ghodssi,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Writing – original draft, Writing – review & editing

  Affiliations Institute for Systems Research, University of Maryland, College Park, Maryland, United States of America, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States of America

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• Behtash Babadi ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: pabshire@umd.edu (PAA); behtash@umd.edu (BB)

  Affiliations Institute for Systems Research, University of Maryland, College Park, Maryland, United States of America, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States of America

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• Pamela Ann Abshire

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: pabshire@umd.edu (PAA); behtash@umd.edu (BB)

  Affiliations Institute for Systems Research, University of Maryland, College Park, Maryland, United States of America, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States of America

  https://orcid.org/0000-0001-9555-453X

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