Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform

• Lijuan Zhou,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Departments of Biological Chemistry, Genentech, Inc., South San Francisco, California, United States of America

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• Fei Cai,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Departments of Biological Chemistry, Genentech, Inc., South San Francisco, California, United States of America

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• Yanjie Li,

  Roles Data curation, Formal analysis

  Affiliation Department of Peptide Therapeutics, Genentech, Inc., South San Francisco, California, United States of America

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• Xinxin Gao,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Peptide Therapeutics, Genentech, Inc., South San Francisco, California, United States of America

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• Yuehua Wei,

  Roles Data curation, Formal analysis

  Affiliation Departments of Biological Chemistry, Genentech, Inc., South San Francisco, California, United States of America

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• Anna Fedorova,

  Roles Data curation

  Affiliation Departments of Biological Chemistry, Genentech, Inc., South San Francisco, California, United States of America

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• Daniel Kirchhofer,

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Departments of Biological Chemistry, Genentech, Inc., South San Francisco, California, United States of America

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• Rami N. Hannoush ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: ramihannoush@gmail.com (RNH); zhang.yingnan@gene.com (YZ)

  Affiliation Department of Early Discovery Biochemistry, Genentech, Inc., South San Francisco, California, United States of America

  https://orcid.org/0000-0001-9343-0955

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• Yingnan Zhang

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ramihannoush@gmail.com (RNH); zhang.yingnan@gene.com (YZ)

  Affiliation Departments of Biological Chemistry, Genentech, Inc., South San Francisco, California, United States of America

  https://orcid.org/0009-0004-1268-0477

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