HEBE project: Healthy aging versus inflamm-aging: The role of physical exercise in modulating the biomarkers of age-associated and environmentally determined chronic diseases, study protocol

• Francesca Bianchi ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization

  Affiliations Department of Biomedical Science for Health, University of Milan, Milan, Italy, Laboratorio Morfologia Umana Applicata, IRCCS Policlinico San Donato, Milan, Italy

  https://orcid.org/0000-0001-5197-5279

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• Elia Mario Biganzoli ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization, Funding acquisition

  * E-mail: elia.biganzoli@unimi.it (EMB); mario.clerici@unimi.it (MC)

  Affiliations Department of Biomedical and Clinical Sciences L. Sacco, Medical Statistics Unit, "Luigi Sacco" University Hospital, University of Milan, Milan, Italy, Data Science Research Center, University of Milan, Milan, Italy

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• Valentina Bollati ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization

  Affiliations EPIGET—Epidemiology, Epigenetics and Toxicology Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, Epidemiology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

  https://orcid.org/0000-0002-0370-9598

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• Mario Clerici ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization, Funding acquisition

  * E-mail: elia.biganzoli@unimi.it (EMB); mario.clerici@unimi.it (MC)

  Affiliations Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy, Don C. Gnocchi Foundation, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Foundation, Milan, Italy

  https://orcid.org/0000-0001-5920-6191

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• Daniela Lucini ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization, Funding acquisition

  Affiliations BIOMETRA Department, University of Milan, Milan, Italy, Exercise Medicine Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy

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• Chiara Mandò ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization

  Affiliation Department of Biomedical and Clinical Sciences L. Sacco, Medical Statistics Unit, "Luigi Sacco" University Hospital, University of Milan, Milan, Italy

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• Federica Rota ,

  Contributed equally to this work with: Francesca Bianchi, Elia Mario Biganzoli, Valentina Bollati, Mario Clerici, Daniela Lucini, Chiara Mandò, Federica Rota

  Roles Conceptualization

  Affiliation EPIGET—Epidemiology, Epigenetics and Toxicology Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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• on behalf of the HEBE Consortium

  ¶Membership of the HEBE Consortium is provided in the Acknowledgments.

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