Comparative study on differential expression analysis methods for single-cell RNA sequencing data with small biological replicates: Based on single-cell transcriptional data of PBMCs from COVID-19 severe patients

• Jie Xue ,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: xjsnow@hdu.edu.cn

  Affiliation Department of Statistics, School of Economics, Hangzhou Dianzi University, Hangzhou, China

  https://orcid.org/0000-0002-3946-1053

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• Xinfan Zhou,

  Roles Data curation, Methodology, Software, Writing – original draft

  Affiliation Department of Statistics, School of Economics, Hangzhou Dianzi University, Hangzhou, China

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• Jing Yang,

  Roles Formal analysis, Writing – original draft

  Affiliation Department of Statistics, School of Economics, Hangzhou Dianzi University, Hangzhou, China

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• Adan Niu

  Roles Methodology, Writing – review & editing

  Affiliation Department of Statistics, School of Economics, Hangzhou Dianzi University, Hangzhou, China

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