Protection of prior SARS-CoV-2 infection, COVID-19 boosters, and hybrid immunity against Omicron severe illness: A population-based cohort study of five million residents in Canada

• Shishi Wu,

  Roles Conceptualization, Methodology, Validation, Writing – original draft

  Affiliation Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

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• Yanhong Li,

  Roles Formal analysis, Writing – review & editing

  Affiliation Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

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• Stefan Baral,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Sharmistha Mishra,

  Roles Methodology, Writing – review & editing

  Affiliations MAP Centre for Urban Health Solutions, St. Michael’s Hospital, Toronto, Ontario, Canada, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, Department of Medicine and Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada

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• Maria Koh,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada

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• Haley Golding,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-5912-5869

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• Jeffrey C. Kwong ,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  ¶‡ XW and JCK are senior authors on this work.

  Affiliations Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada, Public Health Ontario, Toronto, Ontario, Canada, Centre for Vaccine Preventable Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada, University Health Network, Toronto, Ontario, Canada

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• Xiaolin Wei

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: xiaolin.wei@utoronto.ca

  ¶‡ XW and JCK are senior authors on this work.

  Affiliations Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada, Centre for Vaccine Preventable Diseases, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0002-3076-2650

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