CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA

Yunlu Liu; Hongyan Jiang; Keli Hu; Hui Zou; Weiguo Zhang; Jiangtao Liu; Xiaofei Jian

doi:10.1371/journal.pone.0298947

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Open Access

Peer-reviewed

Research Article

CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA

Yunlu Liu ,

Contributed equally to this work with: Yunlu Liu, Hongyan Jiang

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Department of Orthopedics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China
⨯
Hongyan Jiang ,

Contributed equally to this work with: Yunlu Liu, Hongyan Jiang

Roles Conceptualization, Formal analysis, Validation, Writing – review & editing

Affiliation Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
⨯
Keli Hu,

Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – original draft

Affiliation Department of Orthopedics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China
⨯
Hui Zou,

Roles Data curation, Formal analysis, Methodology, Validation

Affiliation Department of Orthopedics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China
⨯
Weiguo Zhang,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Department of Orthopedics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China
⨯
Jiangtao Liu,

Roles Investigation, Project administration, Supervision, Writing – review & editing

Affiliation Department of Orthopedics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China
⨯
Xiaofei Jian

Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: xiaofeijian0417@126.com

Affiliation Department of Orthopedics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China

https://orcid.org/0009-0009-0328-6511

⨯

CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA

Yunlu Liu,
Hongyan Jiang,
Keli Hu,
Hui Zou,
Weiguo Zhang,
Jiangtao Liu,
Xiaofei Jian

Published: April 16, 2024
https://doi.org/10.1371/journal.pone.0298947

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Osteosarcoma cells
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Messenger RNA
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Osteosarcoma
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Protein translation
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