Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype

Lisa Volk-Draper; Shaswati Athaiya; Maria Espinosa Gonzalez; Nihit Bhattarai; Andrew Wilber; Sophia Ran

doi:10.1371/journal.pone.0298465

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Open Access

Peer-reviewed

Research Article

Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype

Lisa Volk-Draper,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

Affiliation Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, United States of America
⨯
Shaswati Athaiya,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, United States of America
⨯
Maria Espinosa Gonzalez,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, United States of America
⨯
Nihit Bhattarai,

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, United States of America
⨯
Andrew Wilber,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliations Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, United States of America, Simmons Cancer Institute, Southern Illinois University School of Medicine, Springfield, IL, United States of America
⨯
Sophia Ran

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sran@siumed.edu

Affiliations Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, United States of America, Simmons Cancer Institute, Southern Illinois University School of Medicine, Springfield, IL, United States of America

https://orcid.org/0000-0003-3958-6099

⨯

Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype

Lisa Volk-Draper,
Shaswati Athaiya,
Maria Espinosa Gonzalez,
Nihit Bhattarai,
Andrew Wilber,
Sophia Ran

Published: April 19, 2024
https://doi.org/10.1371/journal.pone.0298465

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