Can the combination of antiplatelet or alteplase thrombolytic therapy with argatroban benefit patients suffering from acute stroke? a systematic review, meta-analysis, and meta-regression

• Haiyan Xie,

  Roles Conceptualization, Funding acquisition, Resources

  Affiliation Department of Clinical Pharmacy, The Third Hospital of Quzhou, Quzhou, Zhejiang, 324003, China

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• Ying Chen,

  Roles Funding acquisition

  Affiliation Hangzhou Fuyang District Hospital of Traditional Chinese Medicine, Zhejiang, 311499, China

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• Wukun Ge,

  Roles Data curation, Supervision, Writing – original draft

  Affiliation Department of Clinical Pharmacy, Ninghai First Hospital, Zhejiang, 315600, China

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• Xiuping Xu ,

  Roles Data curation, Investigation

  * E-mail: 15695701156@163.com

  Affiliation Department of Emergency Internal Medicine, The Third Hospital of Quzhou, Quzhou, Zhejiang, 324003,China

  https://orcid.org/0009-0001-4493-8792

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• Chengjiang Liu,

  Roles Validation, Visualization, Writing – original draft

  Affiliation Department of General Medicine, Affiliated Anqing First People’s Hospital of Anhui Medical University, HeFei, 246000, China

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• Zhiyong Lan,

  Roles Conceptualization, Funding acquisition

  Affiliation Department of Psychiatry Department, The Third Hospital of Quzhou, Quzhou, Zhejiang, 324003, China

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• Yina Yang

  Roles Investigation, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Ninghai First Hospital, Zhejiang, 315600, China

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