Metabolic-dysfunction associated steatotic liver disease-related diseases, cognition and dementia: A two-sample mendelian randomization study

Yao-Shuang Li; Yu-Ge Xia; Yan-Lan Liu; Wei-Ran Jiang; Hui-Na Qiu; Fan Wu; Jing-Bo Li; Jing-Na Lin

doi:10.1371/journal.pone.0297883

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Open Access

Peer-reviewed

Research Article

Metabolic-dysfunction associated steatotic liver disease-related diseases, cognition and dementia: A two-sample mendelian randomization study

Yao-Shuang Li,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Visualization, Writing – original draft, Writing – review & editing

Affiliations Tianjin Union Medical Center, Tianjin Medical University, Tianjin, China, Department of Endocrinology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China
⨯
Yu-Ge Xia,

Roles Data curation, Formal analysis

Affiliation Geriatric Department, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China
⨯
Yan-Lan Liu,

Roles Data curation, Formal analysis

Affiliation Department of Endocrinology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China
⨯
Wei-Ran Jiang,

Roles Investigation, Methodology

Affiliation Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, New York, United States of America
⨯
Hui-Na Qiu,

Roles Data curation, Formal analysis

Affiliation Department of Endocrinology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China
⨯
Fan Wu,

Roles Data curation, Formal analysis

Affiliation Department of Endocrinology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China
⨯
Jing-Bo Li ,

Roles Supervision, Validation

* E-mail: 13207628978@163.com (JNL); doctorljb@aliyun.com (JBL)

Affiliation Department of Endocrinology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China
⨯
Jing-Na Lin

Roles Funding acquisition, Supervision, Validation, Writing – review & editing

* E-mail: 13207628978@163.com (JNL); doctorljb@aliyun.com (JBL)

Affiliation Department of Endocrinology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China

https://orcid.org/0000-0002-1772-6903

⨯

Metabolic-dysfunction associated steatotic liver disease-related diseases, cognition and dementia: A two-sample mendelian randomization study

Yao-Shuang Li,
Yu-Ge Xia,
Yan-Lan Liu,
Wei-Ran Jiang,
Hui-Na Qiu,
Fan Wu,
Jing-Bo Li,
Jing-Na Lin

Published: February 29, 2024
https://doi.org/10.1371/journal.pone.0297883

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Single nucleotide polymorphisms
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Liver fibrosis
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Cirrhosis
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Alzheimer's disease
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Biopsy
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Liver diseases
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