Jagged 2 inhibition attenuates hypoxia-induced mitochondrial damage and pulmonary hypertension through Sirtuin 1 signaling

• Hanhan Liu,

  Roles Data curation, Investigation, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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• Zhou Pan,

  Roles Formal analysis, Methodology, Project administration, Writing – original draft

  Affiliation DepartmentofRespiratoryandCriticalCareMedicine, Renmin HospitalofWuhan University, Wuhan, China

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• Xiaofeng Wu,

  Roles Project administration, Resources, Software, Supervision, Validation

  Affiliation DepartmentofRespiratoryandCriticalCareMedicine, TaiheHospitalofShiyan, HubeiUniversityofMedicine, Shiyan, China

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• Cheng Gong ,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  * E-mail: 2018203020086@whu.edu.cn (CG); junbuhu_0218@163.com (JH)

  Affiliation Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China

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• Junbo Hu

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: 2018203020086@whu.edu.cn (CG); junbuhu_0218@163.com (JH)

  Affiliation Department of Pathology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  https://orcid.org/0009-0000-9773-7903

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