Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization

• Stephanie E. Martinez,

  Roles Conceptualization, Data curation, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Current address: Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, United States of America

  Affiliation Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

  https://orcid.org/0000-0001-8430-4973

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• Amit V. Pandey,

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Pediatric Endocrinology, Diabetology, and Metabolism, Department of Biomedical Research, University Children’s Hospital Bern, Switzerland and Translational Hormone Research Program, University of Bern, Bern, Switzerland

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• Tania E. Perez Jimenez,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

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• Zhaohui Zhu,

  Roles Investigation, Resources

  Affiliation Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

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• Michael H. Court

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Writing – review & editing

  * E-mail: michael.court@wsu.edu

  Affiliation Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

  https://orcid.org/0000-0002-2122-9977

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