Proliferation, migration and phenotypic transformation of VSMC induced via Hcy related to up-expression of WWP2 and p-STAT3

Xiuyu Wang; Na Gui; Xing Ma; Yue Zeng; Tingrun Mo; Minghao Zhang

doi:10.1371/journal.pone.0296359

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Peer-reviewed

Research Article

Proliferation, migration and phenotypic transformation of VSMC induced via Hcy related to up-expression of WWP2 and p-STAT3

Xiuyu Wang ,

Contributed equally to this work with: Xiuyu Wang, Na Gui, Xing Ma

Roles Data curation, Formal analysis, Methodology, Writing – original draft

Affiliations Department of Pathophysiology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia, P.R. China, Key Laboratory of Metabolic Cardiovascular Diseases Research of National Health Commission, Ningxia Key Laboratory of Vascular Injury and Repair Research, Yinchuan, Ningxia, P.R. China
⨯
Na Gui ,

Contributed equally to this work with: Xiuyu Wang, Na Gui, Xing Ma

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia, P.R. China
⨯
Xing Ma ,

Contributed equally to this work with: Xiuyu Wang, Na Gui, Xing Ma

Roles Data curation, Formal analysis, Methodology

Affiliation Key Laboratory of Metabolic Cardiovascular Diseases Research of National Health Commission, Ningxia Key Laboratory of Vascular Injury and Repair Research, Yinchuan, Ningxia, P.R. China
⨯
Yue Zeng,

Roles Data curation, Formal analysis, Methodology

Affiliation Key Laboratory of Metabolic Cardiovascular Diseases Research of National Health Commission, Ningxia Key Laboratory of Vascular Injury and Repair Research, Yinchuan, Ningxia, P.R. China
⨯
Tingrun Mo,

Roles Data curation

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia, P.R. China
⨯
Minghao Zhang

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Writing – original draft, Writing – review & editing

* E-mail: zhangmh270@163.com

Affiliations Department of Pathophysiology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia, P.R. China, Key Laboratory of Metabolic Cardiovascular Diseases Research of National Health Commission, Ningxia Key Laboratory of Vascular Injury and Repair Research, Yinchuan, Ningxia, P.R. China

https://orcid.org/0009-0005-4347-4569

⨯

Proliferation, migration and phenotypic transformation of VSMC induced via Hcy related to up-expression of WWP2 and p-STAT3

Xiuyu Wang,
Na Gui,
Xing Ma,
Yue Zeng,
Tingrun Mo,
Minghao Zhang

Published: January 2, 2024
https://doi.org/10.1371/journal.pone.0296359

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Protein expression
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Phosphorylation
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Mouse models
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Histones
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Phenotypes
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Transfection
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STAT signaling
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Immunofluorescence staining
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