Direct toxicity of cigarette smoke extract on cardiac function mediated by mitochondrial dysfunction in Sprague-Dawley rat ventricular myocytes and human induced pluripotent stem cell-derived cardiomyocytes

• Sakiko Matsumura ,

  Contributed equally to this work with: Sakiko Matsumura, Jumpei Yasuda

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Pharmacology, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

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• Jumpei Yasuda ,

  Contributed equally to this work with: Sakiko Matsumura, Jumpei Yasuda

  Roles Data curation, Formal analysis, Investigation, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

  ⨯
• Takuya Notomi,

  Roles Data curation, Formal analysis, Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

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• Yoshihiro Suzuki,

  Roles Data curation, Formal analysis, Methodology

  Affiliation R&D Headquarters Development Department, SIBATA Scientific Technology Ltd, Saitama, Japan

  ⨯
• I-Shan Chen,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

  https://orcid.org/0000-0003-3204-3921

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• Daichi Murakami,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

  https://orcid.org/0000-0001-9991-9428

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• Muneki Hotomi,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

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• Tomoe Y. Nakamura

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: tomoen@wakayama-med.ac.jp

  Affiliation Department of Pharmacology, Faculty of Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan

  https://orcid.org/0000-0003-0086-1022

  ⨯