Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody

Michela Centonze; Valentina Fiori; Maciej Kujawski; Lin Li; Patty Wong; Lindsay Williams; Tomas Di Mambro; Sabrina Dominici; Angelo Sparti; John E. Shively; Mauro Magnani

doi:10.1371/journal.pone.0295345

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Open Access

Peer-reviewed

Research Article

Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody

Michela Centonze,

Roles Investigation

Affiliation Department of Biomolecular Science, University of Urbino, Urbino, Italy
⨯
Valentina Fiori,

Roles Funding acquisition

Affiliation Diatheva Srl, Cartoceto (PU), Italy

https://orcid.org/0009-0002-3756-6983

⨯
Maciej Kujawski,

Roles Investigation

Affiliation Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Lin Li,

Roles Investigation

Affiliation Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Patty Wong,

Roles Investigation

Affiliation Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Lindsay Williams,

Roles Investigation, Methodology

Affiliation Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Tomas Di Mambro,

Roles Investigation

Affiliation Diatheva Srl, Cartoceto (PU), Italy
⨯
Sabrina Dominici,

Roles Investigation

Affiliation Diatheva Srl, Cartoceto (PU), Italy
⨯
Angelo Sparti,

Roles Investigation

Affiliation Diatheva Srl, Cartoceto (PU), Italy

https://orcid.org/0009-0003-5496-0250

⨯
John E. Shively ,

Roles Supervision

* E-mail: jshively@coh.org

Affiliation Department of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, California, United States of America

https://orcid.org/0000-0002-7763-770X

⨯
Mauro Magnani

Roles Supervision

Affiliation Department of Biomolecular Science, University of Urbino, Urbino, Italy
⨯

Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody

Michela Centonze,
Valentina Fiori,
Maciej Kujawski,
Lin Li,
Patty Wong,
Lindsay Williams,
Tomas Di Mambro,
Sabrina Dominici,
Angelo Sparti,
John E. Shively

Published: February 12, 2024
https://doi.org/10.1371/journal.pone.0295345

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