A medium-chain fatty acid analogue prevents hepatosteatosis and decreases inflammatory lipid metabolites in a murine model of parenteral nutrition-induced hepatosteatosis

• Bennet S. Cho ,

  Contributed equally to this work with: Bennet S. Cho, Scott C. Fligor

  Roles Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-1440-0019

  ⨯
• Scott C. Fligor ,

  Contributed equally to this work with: Bennet S. Cho, Scott C. Fligor

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Gillian L. Fell,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Jordan D. Secor,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Savas T. Tsikis,

  Roles Formal analysis, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Amy Pan,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America

  ⨯
• Lumeng J. Yu,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Victoria H. Ko,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Duy T. Dao,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Lorenzo Anez-Bustillos,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Thomas I. Hirsch,

  Roles Formal analysis, Writing – review & editing

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Jenny Lund,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0002-0744-8268

  ⨯
• Arild C. Rustan,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway

  ⨯
• David A. Fraser,

  Roles Methodology, Writing – review & editing

  Affiliation NorthSea Therapeutics, Amsterdam, Netherlands

  ⨯
• Kathleen M. Gura,

  Roles Methodology, Writing – review & editing

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pharmacy and the Division of Gastroenterology and Nutrition, Boston Children’s Hospital, Boston, Massachusetts, United States of America

  ⨯
•  [ ... ],
• Mark Puder

  Roles Funding acquisition, Methodology, Supervision, Writing – review & editing

  * E-mail: mark.puder@childrens.harvard.edu

  Affiliations Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-7941-2926

  ⨯
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