COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA.1, BA.2, BA.4/5 or Delta associates with similar illness duration, symptom severity and viral kinetics, irrespective of vaccination history

• Hermaleigh Townsley ,

  Contributed equally to this work with: Hermaleigh Townsley, Joshua Gahir, Timothy W. Russell, David Greenwood

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations The Francis Crick Institute, London, United Kingdom, National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre and NIHR UCLH Clinical Research Facility, London, United Kingdom

  ⨯
• Joshua Gahir ,

  Contributed equally to this work with: Hermaleigh Townsley, Joshua Gahir, Timothy W. Russell, David Greenwood

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations The Francis Crick Institute, London, United Kingdom, National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre and NIHR UCLH Clinical Research Facility, London, United Kingdom

  ⨯
• Timothy W. Russell ,

  Contributed equally to this work with: Hermaleigh Townsley, Joshua Gahir, Timothy W. Russell, David Greenwood

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliation Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0001-5610-6080

  ⨯
• David Greenwood ,

  Contributed equally to this work with: Hermaleigh Townsley, Joshua Gahir, Timothy W. Russell, David Greenwood

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Edward J. Carr,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0001-9343-4593

  ⨯
• Matala Dyke,

  Roles Investigation, Methodology, Project administration, Writing – review & editing

  Affiliations The Francis Crick Institute, London, United Kingdom, National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre and NIHR UCLH Clinical Research Facility, London, United Kingdom

  ⨯
• Lorin Adams,

  Roles Data curation

  Affiliation Worldwide Influenza Centre, The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0001-8357-2327

  ⨯
• Murad Miah,

  Roles Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Bobbi Clayton,

  Roles Data curation

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Callie Smith,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0001-9147-951X

  ⨯
• Mauro Miranda,

  Roles Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0001-5618-883X

  ⨯
• Harriet V. Mears,

  Roles Data curation

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Chris Bailey,

  Roles Data curation, Formal analysis

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• James R. M. Black,

  Roles Data curation, Formal analysis

  Affiliations The Francis Crick Institute, London, United Kingdom, University College London, London, United Kingdom

  ⨯
• Ashley S. Fowler,

  Roles Data curation

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Margaret Crawford,

  Roles Data curation, Investigation, Methodology

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Katalin Wilkinson,

  Roles Data curation, Formal analysis

  Affiliation The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0002-9796-2040

  ⨯
• Matthew Hutchinson,

  Roles Data curation

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Ruth Harvey,

  Roles Data curation

  Affiliations The Francis Crick Institute, London, United Kingdom, Worldwide Influenza Centre, The Francis Crick Institute, London, United Kingdom

  ⨯
• Nicola O’Reilly,

  Roles Data curation, Investigation, Methodology, Project administration

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Gavin Kelly,

  Roles Data curation, Formal analysis, Validation

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Robert Goldstone,

  Roles Data curation, Investigation, Methodology, Project administration, Software

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Rupert Beale,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliations The Francis Crick Institute, London, United Kingdom, University College London, London, United Kingdom, Genotype-to-Phenotype UK National Virology Consortium (G2P-UK)

  ⨯
• Padmasayee Papineni,

  Roles Data curation, Formal analysis, Investigation, Supervision

  Affiliation London Northwest University Healthcare NHS Trust, London, United Kingdom

  ⨯
• Tumena Corrah,

  Roles Data curation, Investigation

  Affiliation London Northwest University Healthcare NHS Trust, London, United Kingdom

  ⨯
• Richard Gilson,

  Roles Data curation, Investigation, Project administration, Resources, Writing – review & editing

  Affiliation Camden and North West London NHS Community Trust, London, United Kingdom

  ⨯
• Simon Caidan,

  Roles Data curation

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• Jerome Nicod,

  Roles Data curation

  Affiliation The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0003-2459-3480

  ⨯
• Steve Gamblin,

  Roles Conceptualization, Data curation, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliation The Francis Crick Institute, London, United Kingdom

  ⨯
• George Kassiotis,

  Roles Data curation, Investigation

  Affiliations The Francis Crick Institute, London, United Kingdom, Department of Infectious Disease, St Mary’s Hospital, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0002-8457-2633

  ⨯
• Vincenzo Libri,

  Roles Conceptualization, Data curation, Supervision, Writing – original draft, Writing – review & editing

  Affiliations National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre and NIHR UCLH Clinical Research Facility, London, United Kingdom, Worldwide Influenza Centre, The Francis Crick Institute, London, United Kingdom

  ⨯
• Bryan Williams,

  Roles Data curation, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliations National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre and NIHR UCLH Clinical Research Facility, London, United Kingdom, Worldwide Influenza Centre, The Francis Crick Institute, London, United Kingdom

  ⨯
• Sonia Gandhi ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ SG, AJK, CS, ECW and DLVB are joint senior authors on this work.

  Affiliations The Francis Crick Institute, London, United Kingdom, University College London, London, United Kingdom

  ⨯
• Adam J. Kucharski ,

  Roles Formal analysis, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ SG, AJK, CS, ECW and DLVB are joint senior authors on this work.

  Affiliation Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

  ⨯
• Charles Swanton ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ SG, AJK, CS, ECW and DLVB are joint senior authors on this work.

  Affiliations The Francis Crick Institute, London, United Kingdom, University College London, London, United Kingdom

  ⨯
• David L. V. Bauer ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: david.bauer@crick.ac.uk (DLVB); emma.wall@crick.ac.uk (EW)

  ¶‡ SG, AJK, CS, ECW and DLVB are joint senior authors on this work.

  Affiliations The Francis Crick Institute, London, United Kingdom, Genotype-to-Phenotype UK National Virology Consortium (G2P-UK)

  https://orcid.org/0000-0003-3052-0368

  ⨯
•  [ ... ],
• Emma C. Wall

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: david.bauer@crick.ac.uk (DLVB); emma.wall@crick.ac.uk (EW)

  ¶‡ SG, AJK, CS, ECW and DLVB are joint senior authors on this work.

  Affiliations The Francis Crick Institute, London, United Kingdom, National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre and NIHR UCLH Clinical Research Facility, London, United Kingdom

  https://orcid.org/0000-0003-2732-4497

  ⨯
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