Preparation of pH-sensitive nanogels bioconjugated with shark antibodies (VNAR) for targeted drug delivery with potential applications in colon cancer therapies

• Lizbeth A. Manzanares-Guevara,

  Roles Conceptualization, Data curation, Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliation Biomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California, México

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• Jahaziel Gasperin-Bulbarela,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Biomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California, México

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• Olivia Cabanillas-Bernal,

  Roles Methodology, Writing – review & editing

  Affiliation Biomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California, México

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• Monserrat Renteria-Maciel,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Biomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California, México

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• Angel Licea-Claverie,

  Roles Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Centro de Graduados e Investigación en Química, Tecnológico Nacional de México/Instituto Tecnológico de Tijuana, Tijuana, Baja California, México

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• Eugenio R. Méndez,

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliation Applied Physics Division, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California, México

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• Alexei F. Licea-Navarro

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: alicea@cicese.mx

  Affiliation Biomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California, México

  https://orcid.org/0000-0003-4022-7405

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