Clinical factors associated with the therapeutic efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma: A multicenter prospective observational study

• Machiko Kai,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Hayato Hikita,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Maesaka Kazuki,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Yuki Tahata,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Kazuma Shinkai,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Akira Doi,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Kazuyoshi Ohkawa,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Osaka, Japan

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• Masanori Miyazaki,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka Police Hospital, Osaka, Osaka, Japan

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• Hisashi Ishida,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Ikeda Municipal Hospital, Ikeda, Osaka, Japan

  ⨯
• Kengo Matsumoto,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Toyonaka Municipal Hospital, Toyonaka, Osaka, Japan

  ⨯
• Yasutoshi Nozaki,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan

  ⨯
• Takayuki Yakushijin,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka General Medical Center, Osaka, Osaka, Japan

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• Ryotaro Sakamori,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, National Hospital Organization Osaka National Hospital, Osaka, Osaka, Japan

  https://orcid.org/0000-0002-1580-607X

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• Akira Kaneko,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Japan Community Healthcare Organization Osaka Hospital, Osaka, Osaka, Japan

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• Sadaharu Iio,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, Hyogo, Japan

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• Takatoshi Nawa,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Higashiosaka City Medical Center, Higashiosaka, Osaka, Japan

  ⨯
• Naruyasu Kakita,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Kaizuka City Hospital, Kaizuka, Osaka, Japan

  ⨯
• Naoki Morishita,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Minoh City Hospital, Minoh, Osaka, Japan

  ⨯
• Naoki Hiramatsu,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka Rosai Hospital, Sakai, Osaka, Japan

  ⨯
• Takeo Usui,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Ashiya Municipal Hospital, Ashiya, Hyogo, Japan

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• Kazuho Imanaka,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Itami City Hospital, Itami, Hyogo, Japan

  ⨯
• Yoshinori Doi,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Otemae Hospital, Osaka, Osaka, Japan

  ⨯
• Mitsuru Sakakibara,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Yao Municipal Hospital, Yao, Osaka, Japan

  ⨯
• Yuichi Yoshida,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Suita Municipal Hospital, Suita, Osaka, Japan

  ⨯
• Tsugiko Oze,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Koga Community Hospital, Yaidu, Shizuoka, Japan

  ⨯
• Takahiro Kodama,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

  ⨯
• Tomohide Tatsumi,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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•  [ ... ],
• Tetsuo Takehara

  Roles Conceptualization, Project administration, Supervision, Writing – review & editing

  * E-mail: takehara@gh.osaka-u.ac.jp

  Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

  https://orcid.org/0000-0001-5036-3457

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