Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females

Kamonwan Chamchoy; Sirapapha Sudsumrit; Jutamas Wongwigkan; Songsak Petmitr; Duantida Songdej; Emily R. Adams; Thomas Edwards; Ubolsree Leartsakulpanich; Usa Boonyuen

doi:10.1371/journal.pone.0294200

Loading metrics

Open Access

Peer-reviewed

Research Article

Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females

Kamonwan Chamchoy,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft

Affiliation Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand
⨯
Sirapapha Sudsumrit,

Roles Investigation

Affiliation Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
⨯
Jutamas Wongwigkan,

Roles Investigation

Affiliation Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
⨯
Songsak Petmitr,

Roles Resources, Writing – review & editing

Affiliation Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
⨯
Duantida Songdej,

Roles Resources, Writing – review & editing

Affiliation Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
⨯
Emily R. Adams,

Roles Methodology, Writing – review & editing

Affiliation Centre for Drugs and Diagnostics Research, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Thomas Edwards,

Roles Methodology, Writing – review & editing

Affiliation Centre for Drugs and Diagnostics Research, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Ubolsree Leartsakulpanich,

Roles Funding acquisition, Writing – review & editing

Affiliation National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand
⨯
Usa Boonyuen

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: usa.boo@mahidol.ac.th; usa.boo@mahidol.edu

Affiliation Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

https://orcid.org/0000-0003-0640-6215

⨯

Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females

Kamonwan Chamchoy,
Sirapapha Sudsumrit,
Jutamas Wongwigkan,
Songsak Petmitr,
Duantida Songdej,
Emily R. Adams,
Thomas Edwards,
Ubolsree Leartsakulpanich,
Usa Boonyuen

Published: November 15, 2023
https://doi.org/10.1371/journal.pone.0294200

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Glucose-6-phosphate dehydrogenase deficiency
Is the Subject Area "Glucose-6-phosphate dehydrogenase deficiency" applicable to this article?

Thanks for your feedback.
Heterozygosity
Is the Subject Area "Heterozygosity" applicable to this article?

Thanks for your feedback.
Mutation detection
Is the Subject Area "Mutation detection" applicable to this article?

Thanks for your feedback.
Mutation
Is the Subject Area "Mutation" applicable to this article?

Thanks for your feedback.
Thai people
Is the Subject Area "Thai people" applicable to this article?

Thanks for your feedback.
Genotyping
Is the Subject Area "Genotyping" applicable to this article?

Thanks for your feedback.
Frameshift mutation
Is the Subject Area "Frameshift mutation" applicable to this article?

Thanks for your feedback.
Introns
Is the Subject Area "Introns" applicable to this article?

Thanks for your feedback.