Optimization and validation of 18F-DCFPyL PET radiomics-based machine learning models in intermediate- to high-risk primary prostate cancer

Wietske I. Luining; Daniela E. Oprea-Lager; André N. Vis; Reindert J. A. van Moorselaar; Remco J. J. Knol; Maurits Wondergem; Ronald Boellaard; Matthijs C. F. Cysouw

doi:10.1371/journal.pone.0293672

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Open Access

Peer-reviewed

Research Article

Optimization and validation of ¹⁸F-DCFPyL PET radiomics-based machine learning models in intermediate- to high-risk primary prostate cancer

Wietske I. Luining ,

Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

* E-mail: w.i.luining@amsterdamumc.nl

Affiliations Department of Urology, Amsterdam University Medical Centers, Prostate Cancer Network Netherlands, Amsterdam, The Netherlands, Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands

https://orcid.org/0000-0003-4590-6589

⨯
Daniela E. Oprea-Lager,

Roles Supervision, Writing – review & editing

Affiliation Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands
⨯
André N. Vis,

Roles Supervision, Writing – review & editing

Affiliation Department of Urology, Amsterdam University Medical Centers, Prostate Cancer Network Netherlands, Amsterdam, The Netherlands
⨯
Reindert J. A. van Moorselaar,

Roles Writing – review & editing

Affiliation Department of Urology, Amsterdam University Medical Centers, Prostate Cancer Network Netherlands, Amsterdam, The Netherlands
⨯
Remco J. J. Knol,

Roles Data curation, Writing – review & editing

Affiliation Department of Nuclear Medicine, Northwest Clinics, Alkmaar, The Netherlands
⨯
Maurits Wondergem,

Roles Data curation, Writing – review & editing

Affiliation Department of Nuclear Medicine, Northwest Clinics, Alkmaar, The Netherlands
⨯
Ronald Boellaard,

Roles Conceptualization, Formal analysis, Methodology, Resources, Software, Supervision, Writing – review & editing

Affiliation Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands
⨯
Matthijs C. F. Cysouw

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands
⨯

Optimization and validation of ¹⁸F-DCFPyL PET radiomics-based machine learning models in intermediate- to high-risk primary prostate cancer

Wietske I. Luining,
Daniela E. Oprea-Lager,
André N. Vis,
Reindert J. A. van Moorselaar,
Remco J. J. Knol,
Maurits Wondergem,
Ronald Boellaard,
Matthijs C. F. Cysouw

Published: November 9, 2023
https://doi.org/10.1371/journal.pone.0293672

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Biopsy
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Positron emission tomography
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Prostate gland
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