Socioeconomic inequalities, psychosocial stressors at work and physician-diagnosed depression: Time-to-event mediation analysis in the presence of time-varying confounders

Ana Paula Bruno Pena-Gralle; Denis Talbot; Xavier Trudel; Alain Milot; Mahée Gilbert-Ouimet; Mathilde Lavigne-Robichaud; Ruth Ndjaboué; Alain Lesage; Sophie Lauzier; Michel Vézina; Johannes Siegrist; Chantal Brisson

doi:10.1371/journal.pone.0293388

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Open Access

Peer-reviewed

Research Article

Socioeconomic inequalities, psychosocial stressors at work and physician-diagnosed depression: Time-to-event mediation analysis in the presence of time-varying confounders

Ana Paula Bruno Pena-Gralle ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ana.paula.bruno.pena.gralle@umontreal.ca

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Faculty of Medicine, Laval University, Québec, Québec, Canada, VITAM – Centre de Recherche en Santé Durable, Québec, Québec, Canada

https://orcid.org/0000-0002-6900-1349

⨯
Denis Talbot,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Faculty of Medicine, Laval University, Québec, Québec, Canada
⨯
Xavier Trudel,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Faculty of Medicine, Laval University, Québec, Québec, Canada
⨯
Alain Milot,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Faculty of Medicine, Laval University, Québec, Québec, Canada
⨯
Mahée Gilbert-Ouimet,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Department of Health Sciences, Université du Québec à Rimouski, Lévis, Québec, Canada
⨯
Mathilde Lavigne-Robichaud,

Roles Conceptualization, Validation, Visualization, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Faculty of Medicine, Laval University, Québec, Québec, Canada
⨯
Ruth Ndjaboué,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation School of Social Work, Sherbrooke University, Sherbrooke, Québec, Canada
⨯
Alain Lesage,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire en santé mentale de Montréal, Montréal, Québec, Canada
⨯
Sophie Lauzier,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Faculty of Pharmacy, Laval University, Québec, Québec, Canada
⨯
Michel Vézina,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Institut National de Santé Publique du Québec, Québec, Canada
⨯
Johannes Siegrist,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Faculty of Medicine, Department of Medical Sociology, Heinrich-Heine-University, Duesseldorf, Germany
⨯
Chantal Brisson

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliations Centre hospitalier universitaire (CHU) de Québec Research Center, Population Health and Optimal Health Practices Unit, Québec, Québec, Canada, Faculty of Medicine, Laval University, Québec, Québec, Canada, VITAM – Centre de Recherche en Santé Durable, Québec, Québec, Canada
⨯

Socioeconomic inequalities, psychosocial stressors at work and physician-diagnosed depression: Time-to-event mediation analysis in the presence of time-varying confounders

Ana Paula Bruno Pena-Gralle,
Denis Talbot,
Xavier Trudel,
Alain Milot,
Mahée Gilbert-Ouimet,
Mathilde Lavigne-Robichaud,
Ruth Ndjaboué,
Alain Lesage,
Sophie Lauzier,
Michel Vézina

Published: October 25, 2023
https://doi.org/10.1371/journal.pone.0293388

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Psychological stress
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