A novel method for quantitation of AAV genome integrity using duplex digital PCR

• Lauren Tereshko ,

  Contributed equally to this work with: Lauren Tereshko, Xiaohui Zhao

  Roles Data curation, Formal analysis, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lauren.tereshko@biogen.com

  Affiliation Analytical Development, Biogen, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0002-3136-753X

  ⨯
• Xiaohui Zhao ,

  Contributed equally to this work with: Lauren Tereshko, Xiaohui Zhao

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Current address: Analytical Development, Vertex Pharmaceuticals, Boston, Massachusetts, United States of America

  Affiliation Analytical Development, Biogen, Cambridge, Massachusetts, United States of America

  ⨯
• Jake Gagnon,

  Roles Formal analysis, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Biostatistics, Biogen, Cambridge, Massachusetts, United States of America

  ⨯
• Tinchi Lin,

  Roles Data curation, Formal analysis, Resources, Software, Validation, Writing – review & editing

  Affiliation Analytics and Data Sciences, Biogen, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0001-5098-6902

  ⨯
• Trevor Ewald,

  Roles Investigation

  Affiliation Analytical Development, Biogen, Cambridge, Massachusetts, United States of America

  ⨯
• Yu Wang,

  Roles Conceptualization

  Affiliation Analytical Development, Biogen, Cambridge, Massachusetts, United States of America

  ⨯
• Marina Feschenko,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision

  Current address: Analytical Development, Vertex Pharmaceuticals, Boston, Massachusetts, United States of America

  Affiliation Analytical Development, Biogen, Cambridge, Massachusetts, United States of America

  ⨯
• Cullen Mason

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Analytical Development, Biogen, Cambridge, Massachusetts, United States of America

  ⨯