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Open Access

Peer-reviewed

Research Article

Acute, subchronic toxicity and genotoxicity studies of JointAlive, a traditional Chinese medicine formulation for knee osteoarthritis

Yuanyuan Wang,

Roles Writing – original draft

Affiliation Chenland Nutritionals, Inc., Irvine, California, United States of America

https://orcid.org/0000-0001-5346-4931

⨯
Li Li ,

Roles Conceptualization, Writing – review & editing

* E-mail: lli@chenalnd.com (LL); dliu@chenland.com (ZL)

Affiliation Chenland Nutritionals, Inc., Irvine, California, United States of America
⨯
Yanling Mu,

Roles Conceptualization

Affiliation School of Pharmacy and Pharmaceutical Sciences, Shandong First Medical University, Jinan, Shandong, China
⨯
Shanglong Wang,

Roles Conceptualization

Affiliation Chenland Nutritionals, Inc., Irvine, California, United States of America
⨯
Xin Li,

Roles Data curation, Formal analysis

Affiliation Chenland Research Institute, Qingdao City, Shandong Province, China
⨯
Jiancheng Zong,

Roles Conceptualization

Affiliation Chenland Research Institute, Qingdao City, Shandong Province, China
⨯
Shengcan Zou,

Roles Conceptualization

Affiliation Chenland Research Institute, Qingdao City, Shandong Province, China
⨯
Zimin Liu ,

Roles Conceptualization

* E-mail: lli@chenalnd.com (LL); dliu@chenland.com (ZL)

Affiliation Chenland Nutritionals, Inc., Irvine, California, United States of America
⨯
Dehai Gao

Roles Conceptualization

Affiliation School of Pharmacy and Pharmaceutical Sciences, Shandong First Medical University, Jinan, Shandong, China
⨯

Acute, subchronic toxicity and genotoxicity studies of JointAlive, a traditional Chinese medicine formulation for knee osteoarthritis

Yuanyuan Wang,
Li Li,
Yanling Mu,
Shanglong Wang,
Xin Li,
Jiancheng Zong,
Shengcan Zou,
Zimin Liu,
Dehai Gao

x

Published: October 17, 2023
https://doi.org/10.1371/journal.pone.0292937

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Toxicity
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Blood counts
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Osteoarthritis
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Total cell counting
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Body weight
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Prostate gland
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Micronuclei
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Toxicity testing
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