ECDD-S16 targets vacuolar ATPase: A potential inhibitor compound for pyroptosis-induced inflammation

• Peeraya Ekchariyawat ,

  Contributed equally to this work with: Peeraya Ekchariyawat, Rattatammanoon Saengfak

  Roles Methodology, Writing – original draft

  Affiliation Department of Microbiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0003-2871-2125

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• Rattatammanoon Saengfak ,

  Contributed equally to this work with: Peeraya Ekchariyawat, Rattatammanoon Saengfak

  Roles Formal analysis, Investigation

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Sucharat Sanongkiet,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom, Thailand

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• Thanapon Charoenwongpaiboon,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom, Thailand

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• Suphasuta Khongpraphan,

  Roles Formal analysis, Investigation, Validation

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Supaporn Mala,

  Roles Formal analysis

  Affiliation Research Office, Faculty of Dentistry, Mahidol University, Bangkok, Thailand

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• Chularat Luangjindarat,

  Roles Formal analysis, Investigation, Validation

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Bumrung Munyoo,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand

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• Napason Chabang,

  Roles Formal analysis, Investigation, Methodology

  Affiliation School of Bioinnovation and Bio-Based Product Intelligence, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Sitthivut Charoensutthivarakul,

  Roles Formal analysis, Investigation, Methodology

  Affiliations Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand, School of Bioinnovation and Bio-Based Product Intelligence, Faculty of Science, Mahidol University, Bangkok, Thailand, Center for Neuroscience, Faculty of Science, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0002-4447-3438

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• Suparerk Borwornpinyo,

  Roles Formal analysis, Investigation, Methodology

  Affiliations Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand, Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Patoomratana Tuchinda,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand

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• Marisa Ponpuak,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Matsayapan Pudla ,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: pongsak.uta@mahidol.ac.th (PU); matsayapan.pud@mahidol.ac.th (MP)

  Affiliation Department of Oral Microbiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand

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• Pongsak Utaisincharoen

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: pongsak.uta@mahidol.ac.th (PU); matsayapan.pud@mahidol.ac.th (MP)

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0002-5522-3127

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