Carvedilol suppresses ryanodine receptor-dependent Ca²⁺ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer’s disease

• Atsushi Hori,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology

  Affiliation Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University, Chiba, Japan

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• Haruka Inaba,

  Roles Data curation, Methodology

  Affiliation Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

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• Takashi Hato,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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• Kimie Tanaka,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

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• Shoichi Sato,

  Roles Data curation, Formal analysis, Methodology, Software

  Affiliation Department of Clinical Engineering, Faculty of Medical Science, Juntendo University, Chiba, Japan

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• Mizuho Okamoto,

  Roles Data curation, Formal analysis, Writing – original draft

  Affiliations Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan, Center for Genomic and Regenerative Medicine, School of Medicine, Juntendo University, Tokyo, Japan

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• Yuna Horiuchi,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University, Chiba, Japan

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• Faith Jessica Paran,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

  https://orcid.org/0000-0003-1149-5048

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• Yoko Tabe,

  Roles Supervision, Visualization

  Affiliation Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

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• Shusuke Mori,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Acute Care and Disaster Medicine, Tokyo Medical and Dental University, Tokyo, Japan

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• Corina Rosales,

  Roles Data curation, Writing – review & editing

  Affiliations Center for Bioenergetics and the Department of Medicine, Houston Methodist Research Institute, Texas, United States of America, Weill Cornell Medicine, New York, New York, United States of America

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• Wado Akamatsu,

  Roles Methodology, Supervision

  Affiliation Center for Genomic and Regenerative Medicine, School of Medicine, Juntendo University, Tokyo, Japan

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• Takashi Murayama,

  Roles Conceptualization, Methodology

  Affiliation Department of Pharmacology, Juntendo University School of Medicine, Tokyo, Japan

  https://orcid.org/0000-0002-3845-2980

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• Nagomi Kurebayashi,

  Roles Methodology

  Affiliation Department of Pharmacology, Juntendo University School of Medicine, Tokyo, Japan

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• Takashi Sakurai,

  Roles Supervision

  Affiliation Department of Pharmacology, Juntendo University School of Medicine, Tokyo, Japan

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• Tomohiko Ai ,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: t-ai@juntendo.ac.jp

  Affiliations Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan, Department of Acute Care and Disaster Medicine, Tokyo Medical and Dental University, Tokyo, Japan, Department of Clinical Laboratory Medicine, Juntendo University Urayasu Hospital, Chiba, Japan

  https://orcid.org/0000-0003-0376-0227

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•  [ ... ],
• Takashi Miida

  Roles Supervision, Visualization

  Affiliations Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University, Chiba, Japan, Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

  https://orcid.org/0000-0002-4294-8030

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