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Open Access

Peer-reviewed

Research Article

Fucoxanthin inhibits cardiac fibroblast transdifferentiation by alleviating oxidative stress through downregulation of BRD4

Jinxia Han ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Writing – original draft, Writing – review & editing

* E-mail: hanjinxia616@sina.com (JH); fisher1688@163.com (HP)

Affiliation Shaoxing Seventh People’s Hospital, Shaoxing, China

https://orcid.org/0009-0008-7058-2604

⨯
Yanfang Zhang,

Roles Investigation, Methodology, Project administration

Affiliation Shaoxing Seventh People’s Hospital, Shaoxing, China
⨯
Haisheng Peng

Roles Conceptualization, Data curation, Funding acquisition, Resources, Writing – review & editing

* E-mail: hanjinxia616@sina.com (JH); fisher1688@163.com (HP)

Affiliation Department of pharmacology, Medical college, Shaoxing University, Shaoxing, China
⨯

Fucoxanthin inhibits cardiac fibroblast transdifferentiation by alleviating oxidative stress through downregulation of BRD4

Jinxia Han,
Yanfang Zhang,
Haisheng Peng

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Published: September 12, 2023
https://doi.org/10.1371/journal.pone.0291469

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Fibrosis
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Protein expression
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Transdifferentiation
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Oxidative stress
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Collagens
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Fibroblasts
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Small interfering RNA
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Stress signaling cascade
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