Selenium inhibits ferroptosis in hyperglycemic cerebral ischemia/reperfusion injury by stimulating the Hippo pathway

Lu Li; Meng Wang; Yan-Mei Ma; Lan Yang; Deng-Hai Zhang; Feng-Ying Guo; Li Jing; Jian-Zhong Zhang

doi:10.1371/journal.pone.0291192

Loading metrics

Open Access

Peer-reviewed

Research Article

Selenium inhibits ferroptosis in hyperglycemic cerebral ischemia/reperfusion injury by stimulating the Hippo pathway

Lu Li ,

Contributed equally to this work with: Lu Li, Meng Wang, Yan-Mei Ma

Roles Conceptualization, Data curation, Writing – original draft

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China

https://orcid.org/0000-0001-9895-6593

⨯
Meng Wang ,

Contributed equally to this work with: Lu Li, Meng Wang, Yan-Mei Ma

Roles Software

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China
⨯
Yan-Mei Ma ,

Contributed equally to this work with: Lu Li, Meng Wang, Yan-Mei Ma

Roles Data curation

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China
⨯
Lan Yang,

Roles Writing – review & editing

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China
⨯
Deng-Hai Zhang,

Roles Writing – review & editing

Affiliation The Shanghai Health Commission Key Lab of AI-Based Management of Inflammation and Chronic Diseases, The Gongli Hospital of Shanghai Pudong New Area, Shanghai, China
⨯
Feng-Ying Guo,

Roles Data curation

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China
⨯
Li Jing ,

Roles Writing – review & editing

* E-mail: 1203220205@qq.com (LJ); zhangjz@nxmu.edu.cn (JZZ)

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China
⨯
Jian-Zhong Zhang

Roles Conceptualization

* E-mail: 1203220205@qq.com (LJ); zhangjz@nxmu.edu.cn (JZZ)

Affiliation Ningxia Key Laboratory of Craniocerebral Diseases, Department of Pathology, School of Basic Medical Science, Ningxia Medical University, Yinchuan, Ningxia, China
⨯

Selenium inhibits ferroptosis in hyperglycemic cerebral ischemia/reperfusion injury by stimulating the Hippo pathway

Lu Li,
Meng Wang,
Yan-Mei Ma,
Lan Yang,
Deng-Hai Zhang,
Feng-Ying Guo,
Li Jing,
Jian-Zhong Zhang

Published: September 8, 2023
https://doi.org/10.1371/journal.pone.0291192

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Selenium
Is the Subject Area "Selenium" applicable to this article?

Thanks for your feedback.
Hyperglycemia
Is the Subject Area "Hyperglycemia" applicable to this article?

Thanks for your feedback.
Fluorescence imaging
Is the Subject Area "Fluorescence imaging" applicable to this article?

Thanks for your feedback.
Nissl staining
Is the Subject Area "Nissl staining" applicable to this article?

Thanks for your feedback.
Cerebral ischemia
Is the Subject Area "Cerebral ischemia" applicable to this article?

Thanks for your feedback.
Immunofluorescence
Is the Subject Area "Immunofluorescence" applicable to this article?

Thanks for your feedback.
Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.