17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier

• Máté Vágvölgyi ,

  Contributed equally to this work with: Máté Vágvölgyi, Dávid Laczkó

  Roles Investigation, Writing – original draft

  Affiliation Institute of Pharmacognosy, University of Szeged, Szeged, Hungary

  ⨯
• Dávid Laczkó ,

  Contributed equally to this work with: Máté Vágvölgyi, Dávid Laczkó

  Roles Investigation, Writing – original draft

  Affiliation Institute of Pharmacognosy, University of Szeged, Szeged, Hungary

  ⨯
• Ana Raquel Santa-Maria,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, Hungary, Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, United States of America

  https://orcid.org/0000-0003-3505-5477

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• Judit P. Vigh,

  Roles Data curation, Investigation

  Affiliations Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, Hungary, Doctoral School of Biology, University of Szeged, Szeged, Hungary

  ⨯
• Fruzsina R. Walter,

  Roles Data curation, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, Hungary

  ⨯
• Róbert Berkecz,

  Roles Investigation

  Affiliation Institute of Pharmaceutical Analysis, University of Szeged, Szeged, Hungary

  ⨯
• Mária A. Deli,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, Hungary

  https://orcid.org/0000-0001-6084-6524

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• Gábor Tóth,

  Roles Data curation, Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation NMR Group, Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Budapest, Hungary

  ⨯
• Attila Hunyadi

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: hunyadi.attila@szte.hu

  Affiliations Institute of Pharmacognosy, University of Szeged, Szeged, Hungary, Interdisciplinary Centre of Natural Products, University of Szeged, Szeged, Hungary, HUN-REN-SZTE Biologically Active Natural Products Research Group, Szeged, Hungary

  ⨯