MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins

Tadahiko Seo; Anthony M. Lowery; Haifang Xu; William Giang; Sergey M. Troyanovsky; Peter A. Vincent; Andrew P. Kowalczyk

doi:10.1371/journal.pone.0290485

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Open Access

Peer-reviewed

Research Article

MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins

Tadahiko Seo,

Roles Data curation, Investigation, Validation, Visualization, Writing – original draft

Affiliation Departments of Dermatology and Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, United States of America

https://orcid.org/0009-0009-3645-7284

⨯
Anthony M. Lowery,

Roles Data curation, Investigation, Visualization, Writing – review & editing

Affiliation Department of Molecular and Cellular Physiology, Albany Medical College, Albany, New York, United States of America
⨯
Haifang Xu,

Roles Data curation, Investigation, Visualization

Affiliation Departments of Dermatology and Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, United States of America
⨯
William Giang,

Roles Software

Affiliation Departments of Dermatology and Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, United States of America

https://orcid.org/0000-0003-0829-259X

⨯
Sergey M. Troyanovsky,

Roles Resources

Affiliations Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America, Department of Cell and Developmental Biology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
Peter A. Vincent,

Roles Funding acquisition, Supervision

Affiliation Department of Molecular and Cellular Physiology, Albany Medical College, Albany, New York, United States of America
⨯
Andrew P. Kowalczyk

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: AndrewKowalczyk@psu.edu

Affiliation Departments of Dermatology and Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, United States of America

https://orcid.org/0000-0001-6438-7863

⨯

MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins

Tadahiko Seo,
Anthony M. Lowery,
Haifang Xu,
William Giang,
Sergey M. Troyanovsky,
Peter A. Vincent,
Andrew P. Kowalczyk

Published: May 9, 2024
https://doi.org/10.1371/journal.pone.0290485

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Cadherins
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Ligases
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Ubiquitin ligases
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Endothelial cells
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Immunofluorescence
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Lysine
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Milk
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Transfection
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