Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model

Yoshiaki Tadokoro; Daisuke Takeda; Aki Murakami; Nanae Yatagai; Izumi Saito; Satomi Arimoto; Yasumasa Kakei; Masaya Akashi; Takumi Hasegawa

doi:10.1371/journal.pone.0290357

Loading metrics

Open Access

Peer-reviewed

Research Article

Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model

Yoshiaki Tadokoro,

Roles Conceptualization, Data curation, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Daisuke Takeda,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Aki Murakami,

Roles Methodology

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Nanae Yatagai,

Roles Methodology

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Izumi Saito,

Roles Methodology

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Satomi Arimoto,

Roles Methodology

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Yasumasa Kakei,

Roles Methodology

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe

https://orcid.org/0000-0002-5997-514X

⨯
Masaya Akashi,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe
⨯
Takumi Hasegawa

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

* E-mail: hasetaku@med.kobe-u.ac.jp

Affiliation Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe

https://orcid.org/0000-0002-7349-7084

⨯

Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model

Yoshiaki Tadokoro,
Daisuke Takeda,
Aki Murakami,
Nanae Yatagai,
Izumi Saito,
Satomi Arimoto,
Yasumasa Kakei,
Masaya Akashi,
Takumi Hasegawa

Published: August 18, 2023
https://doi.org/10.1371/journal.pone.0290357

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Carbon dioxide
Is the Subject Area "Carbon dioxide" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Hypoxia
Is the Subject Area "Hypoxia" applicable to this article?

Thanks for your feedback.
Head and neck cancers
Is the Subject Area "Head and neck cancers" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Metastasis
Is the Subject Area "Metastasis" applicable to this article?

Thanks for your feedback.