What is a minimal clinically important difference for clinical trials in patients with disorders of consciousness? a novel probabilistic approach

• Martin M. Monti ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: monti@ucla.edu

  Affiliations Department of Psychology, University of California Los Angeles, Los Angeles, California, United States of America, Department of Neurosurgery, Brain Injury Research Center, University of California Los Angeles, Los Angeles, California, United States of America

  https://orcid.org/0000-0001-5511-3780

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• Norman M. Spivak,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Department of Neurosurgery, Brain Injury Research Center, University of California Los Angeles, Los Angeles, California, United States of America, UCLA-Caltech Medical Scientist Training Program, David Geffen School of Medicine, UCLA, Los Angeles, California, United States of America

  https://orcid.org/0000-0002-2386-2987

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• Brian L. Edlow,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

  https://orcid.org/0000-0001-7235-8456

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• Yelena G. Bodien

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Harvard Medical School Charlestown, Massachusetts, United States of America

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