A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol

• Manik Chhabra,

  Roles Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology & Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

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• Evan C. Lewis,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation North Toronto Neurology, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-9024-150X

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• Robert Balshaw,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada

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• Breanne Stewart,

  Roles Project administration, Writing – review & editing

  Affiliations Quality Management in Clinical Research (QMCR), University of Alberta, Edmonton, Alberta, Canada, Maternal Infant Child and Youth Research Network (MICYRN), Vancouver, British Columbia, Canada

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• Zina Zaslawski,

  Roles Project administration, Writing – review & editing

  Affiliation George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada

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• Trinity Lowthian,

  Roles Methodology, Writing – review & editing

  Affiliation Youth Research Partners, Childhood Cannabinoid Therapeutics (C4T), Ottawa, Ontario, Canada

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• Zahra Alidina,

  Roles Methodology, Writing – review & editing

  Affiliation Youth Research Partners, Childhood Cannabinoid Therapeutics (C4T), Holland Landing, Ontario, Canada

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• Melila Chesick-Gordis,

  Roles Methodology, Writing – review & editing

  Affiliation Youth Research Partners, Childhood Cannabinoid Therapeutics (C4T), Vancouver, British Columbia, Canada

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• Wenli Xie,

  Roles Project administration, Writing – review & editing

  Affiliation Maternal Infant Child and Youth Research Network (MICYRN), Vancouver, British Columbia, Canada

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• Britt I. Drögemöller,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Galen E. B. Wright,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pharmacology & Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

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• Kathryn A. Birnie,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, University of Calgary, Calgary, Alberta, Canada

  https://orcid.org/0000-0002-8223-8834

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• Katelynn E. Boerner,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-1652-4813

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• Vivian W. L. Tsang,

  Roles Methodology, Writing – review & editing

  Affiliations Maternal Infant Child and Youth Research Network (MICYRN), Vancouver, British Columbia, Canada, Department of Pediatrics, BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-9401-008X

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• Samantha Lee Irwin,

  Roles Methodology, Writing – review & editing

  Affiliation University of Texas at Austin Pediatric Neurosciences at Dell Children’s Pediatric Headache Program, Austin, Texas, United States of America

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• Daniela Pohl,

  Roles Methodology, Writing – review & editing

  Affiliation Division of Neurology, Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada

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• Alexander G. Weil,

  Roles Methodology, Writing – review & editing

  Affiliation Pediatric Neurosurgery, Department of Surgery, Sainte Justine Hospital, University of Montreal, Montreal, Quebec, Canada

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• Erick Sell,

  Roles Methodology, Writing – review & editing

  Affiliation Division of Neurology, Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada

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• Erika Penz,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

  https://orcid.org/0000-0003-2610-8450

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• Amy Robson-MacKay,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Psychiatry, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

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• Sophia Mbabaali,

  Roles Project administration, Writing – review & editing

  Affiliation George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada

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• Stephanie Blackman,

  Roles Project administration, Writing – review & editing

  Affiliations Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, Center for Pediatric Pain Research, IWK Health, Halifax, Nova Scotia, Canada

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• Shanlea Gordon,

  Roles Project administration, Writing – review & editing

  Affiliation Department of Pediatrics, BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-2615-8060

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• Jane Alcorn,

  Roles Methodology, Resources, Writing – review & editing

  Affiliations Cannabinoid Research Initiative of Saskatchewan, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

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• Richard J. Huntsman,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Cannabinoid Research Initiative of Saskatchewan, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Division Pediatric Neurology, Department of Pediatrics, Faculty of Medicine, Dalhousie University, Halifax, Canada

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• Tim F. Oberlander,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada

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• G. Allen Finley,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, Center for Pediatric Pain Research, IWK Health, Halifax, Nova Scotia, Canada

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•  [ ... ],
• Lauren E. Kelly

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  * E-mail: lauren.elyse.kelly@gmail.com

  Affiliation Department of Pharmacology & Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

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