System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma

Renlun Huang; Lang Guo; Chiwei Chen; Yuyang Xiang; Guohao Li; Jieyan Zheng; Yanping Wu; Xiu Yuan; Jianfu Zhou; Wenxi Gao; Songtao Xiang

doi:10.1371/journal.pone.0289418

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Open Access

Peer-reviewed

Research Article

System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma

Renlun Huang ,

Contributed equally to this work with: Renlun Huang, Lang Guo

Roles Methodology, Writing – original draft

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Department of Urology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Lang Guo ,

Contributed equally to this work with: Renlun Huang, Lang Guo

Roles Data curation

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Department of Urology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei University of Chinese Medicine Affiliated Hubei Hospital of Chinese Medicine, Wuhan, Hubei, China
⨯
Chiwei Chen,

Roles Validation

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Department of Urology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Yuyang Xiang,

Roles Validation

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, The Second Clinical College of Southern Medical University, Guangzhou, Guangdong, China
⨯
Guohao Li,

Roles Investigation

Affiliation Department of Urology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei University of Chinese Medicine Affiliated Hubei Hospital of Chinese Medicine, Wuhan, Hubei, China
⨯
Jieyan Zheng,

Roles Methodology

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Department of Urology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Yanping Wu,

Roles Project administration

Affiliation First Clinical College and Affiliated Hospital, Hubei University of Traditional Chinese Medicine, Wuhan, Hubei, China
⨯
Xiu Yuan,

Roles Investigation

Affiliation Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jianfu Zhou,

Roles Formal analysis

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Department of Urology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Wenxi Gao ,

Roles Formal analysis

* E-mail: gwx203@163.com (WG); tonyxst@gzucm.edu.cn (SX)

Affiliation Department of Urology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei University of Chinese Medicine Affiliated Hubei Hospital of Chinese Medicine, Wuhan, Hubei, China
⨯
Songtao Xiang

Roles Conceptualization, Funding acquisition, Writing – review & editing

* E-mail: gwx203@163.com (WG); tonyxst@gzucm.edu.cn (SX)

Affiliations The Research Center of Integrative Cancer Medicine, Discipline of Integrated Chinese and Western Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Department of Urology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China

https://orcid.org/0000-0001-5574-3432

⨯

System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma

Renlun Huang,
Lang Guo,
Chiwei Chen,
Yuyang Xiang,
Guohao Li,
Jieyan Zheng,
Yanping Wu,
Xiu Yuan,
Jianfu Zhou,
Wenxi Gao

Published: August 3, 2023
https://doi.org/10.1371/journal.pone.0289418

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