Systematically uncovering the absorbed effective substances of Radix Scutellaria-licorice drug pair in rat plasma against COVID-19 using a combined UHPLC-Q-TOF-MS analysis and target network pharmacology

• Xuqing Wen ,

  Contributed equally to this work with: Xuqing Wen, Weiwei Xie

  Roles Data curation, Methodology, Software, Writing – original draft

  Affiliation Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, P. R. China

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• Weiwei Xie ,

  Contributed equally to this work with: Xuqing Wen, Weiwei Xie

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, P. R. China

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• Juan Gao,

  Roles Data curation, Formal analysis

  Affiliation Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, P. R. China

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• Dedong Zhang,

  Roles Data curation

  Affiliation Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, P. R. China

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• Mengxin Yang,

  Roles Data curation

  Affiliation Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, Hebei, 050017, P. R. China

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• Zhiqing Zhang,

  Roles Writing – review & editing

  Affiliation Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, P. R. China

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• Yingfeng Du ,

  Roles Writing – review & editing

  * E-mail: yingfengdu@hotmail.com (YD); jinyiran@sohu.com (YJ)

  Affiliation Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, Hebei, 050017, P. R. China

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• Yiran Jin

  Roles Writing – review & editing

  * E-mail: yingfengdu@hotmail.com (YD); jinyiran@sohu.com (YJ)

  Affiliation Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, P. R. China

  https://orcid.org/0000-0001-9496-9346

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