In silico analysis and experimental validation shows negative correlation between miR-1183 and cell cycle progression gene 1 expression in colorectal cancer

Syeda Alina Fatima; Mubeen Tabish Nasim; Ambrin Malik; Saif Ur Rehman; Saboora Waris; Manal Rauf; Syed Salman Ali; Farhan Haq; Hassaan Mehboob Awan

doi:10.1371/journal.pone.0289082

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Open Access

Peer-reviewed

Research Article

In silico analysis and experimental validation shows negative correlation between miR-1183 and cell cycle progression gene 1 expression in colorectal cancer

Syeda Alina Fatima ,

Contributed equally to this work with: Syeda Alina Fatima, Mubeen Tabish Nasim

Roles Formal analysis, Investigation, Writing – original draft

Affiliation Department of Biosciences, Cancer Genetics and Epigenetics Lab, COMSATS University Islamabad, Islamabad, Pakistan
⨯
Mubeen Tabish Nasim ,

Contributed equally to this work with: Syeda Alina Fatima, Mubeen Tabish Nasim

Roles Investigation, Writing – original draft

Affiliation Department of Biosciences, Cancer Genetics and Epigenetics Lab, COMSATS University Islamabad, Islamabad, Pakistan
⨯
Ambrin Malik,

Roles Methodology

Affiliation Department of Biosciences, Cancer Genetics and Epigenetics Lab, COMSATS University Islamabad, Islamabad, Pakistan
⨯
Saif Ur Rehman,

Roles Writing – review & editing

Affiliation Department of Biosciences, Cancer Genetics and Epigenetics Lab, COMSATS University Islamabad, Islamabad, Pakistan
⨯
Saboora Waris,

Roles Resources

Affiliation Maroof International Hospital, Islamabad, Pakistan
⨯
Manal Rauf,

Roles Resources

Affiliation Pakistan Institute of Medical Sciences, Islamabad, Pakistan
⨯
Syed Salman Ali,

Roles Resources

Affiliations Combined Military Hospital, Kharian, Pakistan, Department of Cellular Pathology, Royal London Hospital, Barts Health, NHS Trust, London, United Kingdom
⨯
Farhan Haq,

Roles Conceptualization, Supervision

Affiliations Department of Biosciences, Cancer Genetics and Epigenetics Lab, COMSATS University Islamabad, Islamabad, Pakistan, Division of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden
⨯
Hassaan Mehboob Awan

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: hassaan.awan@comsats.edu.pk

Affiliation Department of Biosciences, Cancer Genetics and Epigenetics Lab, COMSATS University Islamabad, Islamabad, Pakistan

https://orcid.org/0000-0002-8245-8909

⨯

In silico analysis and experimental validation shows negative correlation between miR-1183 and cell cycle progression gene 1 expression in colorectal cancer

Syeda Alina Fatima,
Mubeen Tabish Nasim,
Ambrin Malik,
Saif Ur Rehman,
Saboora Waris,
Manal Rauf,
Syed Salman Ali,
Farhan Haq,
Hassaan Mehboob Awan

Published: August 4, 2023
https://doi.org/10.1371/journal.pone.0289082

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Colorectal cancer
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MicroRNAs
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Hepatocellular carcinoma
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Gastric cancer
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Lung and intrathoracic tumors
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Microarrays
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Breast cancer
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Gene expression
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