Analytical validation, sample stability, and clinical evaluation of a new high-sensitivity cardiac troponin I immunoassay for use in dogs, with comparison to a previous ultrasensitive assay

Sonya Wesselowski; Jonathan Lidbury; Ashley B. Saunders; Sonya G. Gordon; Jan S. Suchodolski; Joerg M. Steiner

doi:10.1371/journal.pone.0288801

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Open Access

Peer-reviewed

Research Article

Analytical validation, sample stability, and clinical evaluation of a new high-sensitivity cardiac troponin I immunoassay for use in dogs, with comparison to a previous ultrasensitive assay

Sonya Wesselowski ,

Roles Conceptualization, Data curation, Investigation, Writing – original draft, Writing – review & editing

* E-mail: swesselowski@cvm.tamu.edu

Affiliation Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States of America

https://orcid.org/0000-0002-0637-8288

⨯
Jonathan Lidbury,

Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States of America
⨯
Ashley B. Saunders,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States of America
⨯
Sonya G. Gordon,

Roles Conceptualization, Resources, Writing – review & editing

Affiliation Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States of America
⨯
Jan S. Suchodolski,

Roles Conceptualization, Resources, Writing – review & editing

Affiliation Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States of America
⨯
Joerg M. Steiner

Roles Conceptualization, Resources, Writing – review & editing

Affiliation Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States of America
⨯

Analytical validation, sample stability, and clinical evaluation of a new high-sensitivity cardiac troponin I immunoassay for use in dogs, with comparison to a previous ultrasensitive assay

Sonya Wesselowski,
Jonathan Lidbury,
Ashley B. Saunders,
Sonya G. Gordon,
Jan S. Suchodolski,
Joerg M. Steiner

Published: July 18, 2023
https://doi.org/10.1371/journal.pone.0288801

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Dogs
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Troponin
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Congenital heart defects
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Veterinary diseases
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