Effectiveness of oral prednisone tapering following intravenous methylprednisolone for acute optic neuritis in multiple sclerosis

• Adi Wilf-Yarkoni ,

  Contributed equally to this work with: Adi Wilf-Yarkoni, Kristina Feldmann

  Roles Conceptualization, Data curation, Investigation, Project administration, Resources, Writing – original draft

  Affiliations Neuroimmunology Unit, Department of Neurology, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  https://orcid.org/0000-0002-2584-5793

  ⨯
• Kristina Feldmann ,

  Contributed equally to this work with: Adi Wilf-Yarkoni, Kristina Feldmann

  Roles Conceptualization, Data curation, Writing – original draft

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Department of Emergency and Acute Medicine, Campus Mitte and Virchow, Charité –Universitätsmedizin Berlin, Berlin, Germany

  ⨯
• Kerstin Rubarth,

  Roles Formal analysis, Writing – review & editing

  Affiliations Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Charité Universitaetsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Institute of Biometry and Clinical Epidemiology, Berlin, Germany

  https://orcid.org/0000-0002-6174-6346

  ⨯
• Eva-Maria Dorsch,

  Roles Data curation, Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯
• Rebekka Rust,

  Roles Data curation, Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Berlin Institute of Health (BIH), Berlin, Germany

  ⨯
• Ilia Urman,

  Roles Data curation, Writing – review & editing

  Affiliations Neuroimmunology Unit, Department of Neurology, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  ⨯
• Mark A. Hellmann,

  Roles Data curation, Writing – review & editing

  Affiliations Neuroimmunology Unit, Department of Neurology, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  ⨯
• Yitzhak Friedman,

  Roles Data curation, Writing – review & editing

  Affiliations Neuroimmunology Unit, Department of Neurology, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  ⨯
• Itay Lotan,

  Roles Data curation, Writing – review & editing

  Affiliations Neuroimmunology Unit, Department of Neurology, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  https://orcid.org/0000-0002-4015-9783

  ⨯
• Omer Bialer,

  Roles Data curation, Writing – review & editing

  Affiliations Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, Felsenstein Medical Research Center, Tel Aviv University, Tel Aviv, Israel, Neuro-Ophthalmology Unit, Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel

  https://orcid.org/0000-0002-9979-7990

  ⨯
• Gilberto Solorza Buenrostro,

  Roles Data curation, Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯
• Hanna G. Zimmermann,

  Roles Data curation, Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯
• Carla Leutloff,

  Roles Data curation, Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯
• Tanja Schmitz-Hübsch,

  Roles Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯
• Friedemann Paul,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯
• Susanna Asseyer ,

  Roles Conceptualization, Data curation, Supervision, Writing – original draft

  * E-mail: susanna.asseyer@charite.de

  ¶‡ SA and HS-K also contributed equally to this work.

  Affiliations Experimental and Clinical Research Center, a Cooperation Between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin, Berlin, Germany, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, Neuroscience Clinical Research Center, Charité –Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  https://orcid.org/0000-0001-6289-1791

  ⨯
•  [ ... ],
• Hadas Stiebel-Kalish

  Roles Conceptualization, Data curation, Supervision, Writing – original draft

  ¶‡ SA and HS-K also contributed equally to this work.

  Affiliations Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, Felsenstein Medical Research Center, Tel Aviv University, Tel Aviv, Israel, Neuro-Ophthalmology Unit, Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel

  https://orcid.org/0000-0001-7715-6706

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