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Open Access
Peer-reviewed
Research Article
Lumicitabine, an orally administered nucleoside analog, in infants hospitalized with respiratory syncytial virus (RSV) infection: Safety, efficacy, and pharmacokinetic results
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Abbie Oey,
Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – review & editing
Affiliation Janssen Research & Development, LLC, South San Francisco, California, United States of America
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Matthew McClure,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – review & editing
Current address: Aligos Therapeutics, South San Francisco, California, United States of America
Affiliation Janssen Research & Development, LLC, South San Francisco, California, United States of America
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Julian A. Symons,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Writing – review & editing
Current address: Aligos Therapeutics, South San Francisco, California, United States of America
Affiliation Janssen Research & Development, LLC, South San Francisco, California, United States of America
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Sushmita Chanda,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing
Current address: Aligos Therapeutics, South San Francisco, California, United States of America
Affiliation Janssen Research & Development, LLC, South San Francisco, California, United States of America
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John Fry,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing
Current address: Aligos Therapeutics, South San Francisco, California, United States of America
Affiliation Janssen Research & Development, LLC, South San Francisco, California, United States of America
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Patrick F. Smith,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Certara Strategic Consulting, Parsippany, New Jersey, United States of America
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Kathia Luciani,
Roles Investigation, Project administration, Writing – review & editing
Affiliation Department of Infectious Diseases Hospital de Especialidades Pediátricas Omar Torrijos Herrera, Panama City, Panama
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Michael Fayon,
Roles Investigation, Project administration, Supervision, Writing – review & editing
Affiliation CHU de Bordeaux, Pneumologie pédiatrique, CIC 1401 (INSERM), Hôpital Pellegrin-Enfants, Bordeaux Cedex, France
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Kulkanya Chokephaibulkit,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Rattapon Uppala,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Department of Pediatrics, Khon Kaen University, Khon Kaen, Thailand
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Jolanta Bernatoniene,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Paediatric Infectious Disease and Immunology Department, Bristol Royal Hospital for Children, Bristol, United Kingdom
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Kenji Furuno,
Roles Investigation, Supervision, Writing – review & editing
Affiliation General Pediatrics & Interdisciplinary Medicine Fukuoka Children’s Hospital, Fukuoka, Japan
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Thorsten Stanley,
Roles Investigation, Supervision, Writing – review & editing
Affiliation Department of Paediatrics, University of Otago, Wellington, New Zealand
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Dymphy Huntjens,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – review & editing
Affiliation Janssen Research & Development, Beerse, Belgium
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James Witek ,
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: jameswitek@gmail.com
Affiliation Janssen Research & Development, LLC, Titusville, New Jersey, United States of America
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on behalf of the 503 and RSV2004 Study Groups
¶Full list of RSV503 and RSV2004 Study Groups is provided in the Acknowledgments.
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Lumicitabine, an orally administered nucleoside analog, in infants hospitalized with respiratory syncytial virus (RSV) infection: Safety, efficacy, and pharmacokinetic results
- Abbie Oey,
- Matthew McClure,
- Julian A. Symons,
- Sushmita Chanda,
- John Fry,
- Patrick F. Smith,
- Kathia Luciani,
- Michael Fayon,
- Kulkanya Chokephaibulkit,
- Rattapon Uppala
- Published: July 19, 2023
- https://doi.org/10.1371/journal.pone.0288271