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Intraperitoneal transplant of Hepatocytes co-Encapsulated with mesenchymal stromal cells in modified alginate microbeads for the treatment of acute Liver failure in Pediatric patients (HELP)—An open-label, single-arm Simon’s two stage phase 1 study protocol
- Emer Fitzpatrick,
- Celine Filippi,
-
Barath Jagadisan,
Roles Methodology, Project administration, Supervision, Writing – review & editing
Affiliations Pediatric Liver GI and Nutrition Centre and Mowat Labs, King’s College Hospital, London, United Kingdom, King’s College London, London, United Kingdom
⨯ - Dharshene Shivapatham,
- Hanish Anand,
- Mike Lyne,
- Katherine-Daisy Stroud,
- Rebecca Newton ,
- Marc DeLord,
- Abdel Douiri,
- Anil Dhawan
https://orcid.org/0000-0002-2108-9054
Intraperitoneal transplant of Hepatocytes co-Encapsulated with mesenchymal stromal cells in modified alginate microbeads for the treatment of acute Liver failure in Pediatric patients (HELP)—An open-label, single-arm Simon’s two stage phase 1 study protocol
- Emer Fitzpatrick,
- Celine Filippi,
- Barath Jagadisan,
- Dharshene Shivapatham,
- Hanish Anand,
- Mike Lyne,
- Katherine-Daisy Stroud,
- Rebecca Newton,
- Marc DeLord,
- Abdel Douiri
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- Published: July 25, 2023
- https://doi.org/10.1371/journal.pone.0288185