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Open Access
Peer-reviewed
Research Article
The role of flavin mononucleotide (FMN) as a potentially clinically relevant biomarker to predict the quality of kidney grafts during hypothermic (oxygenated) machine perfusion
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Fenna E. M. van de Leemkolk ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: f.e.m.van_de_leemkolk@lumc.nl
Affiliations Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands, LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom
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M. Letizia Lo Faro,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom
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Sadr Shaheed,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom
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John F. Mulvey,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom
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Volkert A. L. Huurman,
Roles Writing – review & editing
Affiliations Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands, LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands
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Ian P. J. Alwayn,
Roles Writing – review & editing
Affiliations Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands, LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands
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Hein Putter,
Roles Methodology
Affiliations LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands
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Ina Jochmans,
Roles Writing – review & editing
Affiliations Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium, Transplantation Research Group, Lab of Abdominal Transplantation, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Belgium
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Jan H. N. Lindeman ,
Contributed equally to this work with: Jan H. N. Lindeman, Rutger J. Ploeg
Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands, LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands
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Rutger J. Ploeg ,
Contributed equally to this work with: Jan H. N. Lindeman, Rutger J. Ploeg
Roles Conceptualization, Methodology, Supervision, Writing – review & editing
Affiliations LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom
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on behalf of the COMPARE Trial Collaboration and the Consortium for Organ Preservation in Europe (COPE)
¶Membership of the COMPARE Trial Collaboration and the Consortium for Organ Preservation in Europe is provided in the Acknowledgments.
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The role of flavin mononucleotide (FMN) as a potentially clinically relevant biomarker to predict the quality of kidney grafts during hypothermic (oxygenated) machine perfusion
- Fenna E. M. van de Leemkolk,
- M. Letizia Lo Faro,
- Sadr Shaheed,
- John F. Mulvey,
- Volkert A. L. Huurman,
- Ian P. J. Alwayn,
- Hein Putter,
- Ina Jochmans,
- Jan H. N. Lindeman,
- Rutger J. Ploeg
- Published: June 23, 2023
- https://doi.org/10.1371/journal.pone.0287713