Spontaneous urinary bladder regeneration after subtotal cystectomy increases YAP/WWTR1 signaling and downstream BDNF expression: Implications for smooth muscle injury responses

• Karen J. Aitken ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: karen.aitken@alumni.utoronto.ca (KJA); darius.bagli@sickkids.ca (DB)

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0003-2995-0205

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• Priyank Yadav ,

  Contributed equally to this work with: Priyank Yadav, Martin Sidler

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Department of Urology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, Urology Division, Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada

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• Martin Sidler ,

  Contributed equally to this work with: Priyank Yadav, Martin Sidler

  Roles Conceptualization, Investigation, Methodology

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Urology Division, Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada, Division Chief, Paediatric and Neonatal Surgeon, University Hospital Ulm, Ulm, Baden-Württemberg, Germany

  https://orcid.org/0000-0002-3562-2972

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• Thenuka Thanabalasingam,

  Roles Formal analysis, Investigation, Visualization

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Human Biology Programme, Faculty of Arts and Sciences, University of Toronto, Toronto, Ontario, Canada

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• Tabina Ahmed,

  Roles Visualization, Writing – review & editing

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Human Biology Programme, Faculty of Arts and Sciences, University of Toronto, Toronto, Ontario, Canada

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• Prateek Aggarwal,

  Roles Formal analysis, Investigation, Visualization

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Human Biology Programme, Faculty of Arts and Sciences, University of Toronto, Toronto, Ontario, Canada

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• Shing Tai Yip,

  Roles Formal analysis, Investigation

  Affiliation Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada

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• Nefateri Jeffrey,

  Roles Formal analysis, Investigation

  Affiliation Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada

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• Jia-Xin Jiang,

  Roles Formal analysis, Investigation

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Aliza Siebenaller,

  Roles Formal analysis, Investigation

  Affiliation Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada

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• Chris Sotiropoulos,

  Roles Methodology

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Human Biology Programme, Faculty of Arts and Sciences, University of Toronto, Toronto, Ontario, Canada, Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Ryan Huang,

  Roles Visualization

  Affiliation Human Biology Programme, Faculty of Arts and Sciences, University of Toronto, Toronto, Ontario, Canada

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• David Minh Quynh Le,

  Roles Investigation

  Affiliation Human Biology Programme, Faculty of Arts and Sciences, University of Toronto, Toronto, Ontario, Canada

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• Paul Delgado-Olguin,

  Roles Conceptualization, Resources, Supervision

  Affiliations Translational Medicine Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0002-5355-247X

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• Darius Bagli

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: karen.aitken@alumni.utoronto.ca (KJA); darius.bagli@sickkids.ca (DB)

  Affiliations Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada, Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Urology Division, Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada, Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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