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Open Access
Peer-reviewed
Research Article
The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK-mediated apoptosis in unilateral ureteral obstruction
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Jun Ding ,
Contributed equally to this work with: Jun Ding, Sheng Cui
Roles Conceptualization, Data curation, Writing – original draft
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Sheng Cui ,
Contributed equally to this work with: Jun Ding, Sheng Cui
Roles Conceptualization, Data curation, Supervision
Affiliations Department of Nephrology, Yanbian University Hospital, Yanji, China, Department of Internal Medicine, Transplantation Research Center, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea
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Song Yu Li,
Roles Data curation, Methodology, Project administration
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Lin Yan Cui,
Roles Data curation, Project administration
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Qi Yan Nan,
Roles Data curation, Project administration
Affiliation Department of Intensive Care Unit, Yanbian University Hospital, Yanji, China
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Xue Jing Lin,
Roles Data curation, Project administration
Affiliation Department of Radionuclide Medicine, Yanbian University Hospital, Yanji, China
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Mei Ying Xuan,
Roles Data curation, Project administration
Affiliation Department of Health Examination Central, Yanbian University, Yanji, China
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Jian Jin,
Roles Investigation
Affiliation Department of General Practice, Yanbian University Hospital, Yanji, China
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Shang Guo Piao,
Roles Data curation, Funding acquisition, Project administration
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Yu Ji Jiang,
Roles Data curation, Project administration
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Hai Lan Zheng,
Roles Project administration
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Ji Zhe Jin ,
Roles Project administration
* E-mail: jhcui@suda.edu.cn (JHC); lican@ybu.edu.cn (CL); jzhjinmd@ybu.edu.cn (JZJ)
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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Byung Ha Chung,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Internal Medicine, Transplantation Research Center, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Department of Internal Medicine, Division of Nephrology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
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Chul Woo Yang,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Internal Medicine, Transplantation Research Center, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Department of Internal Medicine, Division of Nephrology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
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Jing Hao Cui ,
Roles Conceptualization, Writing – review & editing
* E-mail: jhcui@suda.edu.cn (JHC); lican@ybu.edu.cn (CL); jzhjinmd@ybu.edu.cn (JZJ)
Affiliation College of Pharmaceutical Sciences, Soochow University, Jiangsu Prov., Suzhou, China
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Can Li
Roles Conceptualization, Writing – review & editing
* E-mail: jhcui@suda.edu.cn (JHC); lican@ybu.edu.cn (CL); jzhjinmd@ybu.edu.cn (JZJ)
Affiliation Department of Nephrology, Yanbian University Hospital, Yanji, China
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The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK-mediated apoptosis in unilateral ureteral obstruction
- Jun Ding,
- Sheng Cui,
- Song Yu Li,
- Lin Yan Cui,
- Qi Yan Nan,
- Xue Jing Lin,
- Mei Ying Xuan,
- Jian Jin,
- Shang Guo Piao,
- Yu Ji Jiang
- Published: June 13, 2023
- https://doi.org/10.1371/journal.pone.0286903