New oncogenic functions of LINE1 retroelement as a ceRNA for tumor suppressive microRNA miR-126 on ENPP5

Kang-Hoon Lee; Hyeon-Ji Hwang; Yeo-Jin Im; A-Reum Nam; Jeong-Woon Lee; Je-Yoel Cho

doi:10.1371/journal.pone.0286814

Loading metrics

Open Access

Peer-reviewed

Research Article

New oncogenic functions of LINE1 retroelement as a ceRNA for tumor suppressive microRNA miR-126 on ENPP5

Kang-Hoon Lee ,

Contributed equally to this work with: Kang-Hoon Lee, Hyeon-Ji Hwang

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Current address: GeneOne Life Science, Seoul, Korea

Affiliation Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul, Korea
⨯
Hyeon-Ji Hwang ,

Contributed equally to this work with: Kang-Hoon Lee, Hyeon-Ji Hwang

Roles Validation

Affiliations Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul, Korea, Comparative Medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Yeo-Jin Im,

Roles Formal analysis, Validation

Affiliations Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul, Korea, Comparative Medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
⨯
A-Reum Nam,

Roles Formal analysis

Affiliations Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul, Korea, Comparative Medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Jeong-Woon Lee,

Roles Formal analysis

Affiliations Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul, Korea, Comparative Medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Je-Yoel Cho

Roles Funding acquisition, Supervision, Writing – review & editing

* E-mail: jeycho@snu.ac.kr

Affiliations Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul, Korea, Comparative Medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea

https://orcid.org/0000-0003-1030-3577

⨯

New oncogenic functions of LINE1 retroelement as a ceRNA for tumor suppressive microRNA miR-126 on ENPP5

Kang-Hoon Lee,
Hyeon-Ji Hwang,
Yeo-Jin Im,
A-Reum Nam,
Jeong-Woon Lee,
Je-Yoel Cho

Published: June 23, 2023
https://doi.org/10.1371/journal.pone.0286814

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Human genomics
Is the Subject Area "Human genomics" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Transcriptome analysis
Is the Subject Area "Transcriptome analysis" applicable to this article?

Thanks for your feedback.