Metabolomic and transcriptomic analyses of Fmo5^-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism

• Ian R. Phillips ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: e.shephard@ucl.ac.uk (EAS); i.r.phillips@ucl.ac.uk (IRP)

  Affiliations Department of Structural and Molecular Biology, University College London, London, United Kingdom, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

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• Sunil Veeravalli,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Structural and Molecular Biology, University College London, London, United Kingdom

  https://orcid.org/0000-0002-9652-8461

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• Sanjay Khadayate,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation MRC London Institute of Medical Sciences (LMS), London, United Kingdom

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• Elizabeth A. Shephard

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: e.shephard@ucl.ac.uk (EAS); i.r.phillips@ucl.ac.uk (IRP)

  Affiliation Department of Structural and Molecular Biology, University College London, London, United Kingdom

  https://orcid.org/0000-0003-4905-0562

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